Claudin 5 Recombinant Rabbit Monoclonal Antibody [JM11-22] — image 1 of 3

Product details

Claudin 5 Recombinant Rabbit Monoclonal Antibody [JM11-22]

Catalog number ET1703-58

Discontinued

Price for ET1703-58

Size / count 100 µL

This variant is discontinued and cannot be added to your cart.

About this product

The claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Three classes of proteins are known to localize to tight junctions, including the claudins, Occludin and Junction adhesion molecule. Claudins, which consist of four transmembrane domains and two extracellular loops make up tight junction strands. Claudin expression is highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions. Claudin-5 is expressed in the endothelial junctions of the rat liver and in junctions of acinar cells of the pancreas. Human Claudin-5 is abundantly expressed in adult lung, heart and skeletal muscle and is deleted in patients with velocardiofacial syndrone, which is characterized by cleft palate, facial dysmorphology and conotruncal heart defects.

Specifications

Catalog number: ET1703-58
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
CAS Number: 9000-83-3
Product Name Alternative: Androgen withdrawal and apoptosis induced protein RVP1 like antibody AWAL antibody BEC 1 antibody BEC1 antibody Claudin 5 (transmembrane protein deleted in velocardiofacial syndrome) antibody Claudin-5 antibody Claudin5 antibody CLD5_HUMAN antibody CLDN 5 antibody Cldn5 antibody CPETR L1 antibody CPETRL 1 antibody CPETRL1 antibody TMDVCF antibody TMVCF antibody Transmembrane protein deleted in VCFS antibody Transmembrane protein deleted in velocardiofacial syndrome antibody
Abbreviation: TMDVCF, CLDN5
Swiss Prot: O00501 Human
Cellular Locus: Cell junction. Cell membrane.
Host: Rabbit
Species Reactivity: Human
Immunogen: Synthetic peptide within Human Claudin 5 aa 191-214 / 218.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P
Positive Control: Human brain tissue lysate, human lung tissue lysate, human kidney tissue lysate, human tonsil tissue, human kidney tissue, human lung tissue, human uterus tissue, human lymph nodes tissue
Concentration: 1 mg/mL
Dilution: WB: 1:5,000 ;IHC-P: 1:50-1:200
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 23 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Claudin 5 Recombinant Rabbit Monoclonal Antibody [JM11-22]?

The catalog number for Claudin 5 Recombinant Rabbit Monoclonal Antibody [JM11-22] is ET1703-58.

Is Claudin 5 Recombinant Rabbit Monoclonal Antibody [JM11-22] in stock?

Claudin 5 Recombinant Rabbit Monoclonal Antibody [JM11-22] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Claudin 5 Recombinant Rabbit Monoclonal Antibody [JM11-22] used for?

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.