ADAM10 Recombinant Rabbit Monoclonal Antibody [JM32-11]

Catalog number ET1703-60

Price for ET1703-60

Size / count 100 µL

About this product

ADAM (a disintegrin and metalloprotease) proteins are a family of over 30 membrane-anchored, glycosylated, Zn2+ dependent proteases that are involved in cell-cell, cell-matrix interface related processes including fertilization, muscle fusion, secretion of TNFα (tumor necrosis factor α), and modulation of the neurogenic function of Notch and Delta. ADAM proteins possess a signal-domain, a pro-domain, a metalloprotease domain, a disintegrin domain (integrin ligand) a cysteine-rich region, an epidermal growth factor-like domain, a transmembrane domain and a cytoplasmic tail. ADAMs are expressed in brain, testis, epididymis, ovary, breast, placenta, liver, heart, lung, bone and muscle, and catalyze proteolysis, adhesion, fusion and intracellular signaling. ADAM10 is a TNF-processing enzyme that cleaves pro-TNF, a membrane-bound precusor protein, at Ala 76-Val 77, which causes membrane shedding of soluble TNF.

Specifications

Catalog number: ET1703-60
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: A disintegrin and metalloprotease domain 10 antibody A disintegrin and metalloproteinase domain 10 antibody AD 10 antibody AD10 antibody AD18 antibody ADA10_HUMAN antibody ADAM 10 antibody ADAM metallopeptidase domain 10 antibody ADAM10 antibody CD 156c antibody CD156c antibody CD156c antigen antibody CDw156 antibody disintegrin and metalloproteinase domain containing protein 10 antibody Disintegrin and metalloproteinase domain-containing protein 10 antibody HsT 18717 antibody HsT18717 antibody Kuz antibody Kuzbanian antibody Kuzbanian protein homolog antibody Kuzbanian, Drosophila, homolog of antibody MADM antibody Mammalian disintegrin metalloprotease antibody Mammalian disintegrin-metalloprotease antibody RAK antibody
Abbreviation: ADAM 10
Swiss Prot: O14672 Human, O35598 Mouse, Q10743 Rat
Cellular Locus: Cell membrane. Endomembrane system.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within Human ADAM10 aa 715-748 / 748.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IP, IHC-P
Positive Control: Jurkat cell lysate, HeLa cell lysate, human lung tissue lysate, RAW264.7 cell lysate, mouse placenta tissue lysate, mouse brain tissue lysate, rat brain tissue lysate, rat spleen tissue lysate, human thyroid carcinoma tissue, human stomach tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:2,000 ;IP: 1:10-1:50 ;IHC-P: 1:100
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 84 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for ADAM10 Recombinant Rabbit Monoclonal Antibody [JM32-11]?

The catalog number for ADAM10 Recombinant Rabbit Monoclonal Antibody [JM32-11] is ET1703-60.

What sizes are available for ADAM10 Recombinant Rabbit Monoclonal Antibody [JM32-11]?

ADAM10 Recombinant Rabbit Monoclonal Antibody [JM32-11] is available in the following size(s): 100 µL.

Is ADAM10 Recombinant Rabbit Monoclonal Antibody [JM32-11] in stock?

ADAM10 Recombinant Rabbit Monoclonal Antibody [JM32-11] is currently made to order / not held in immediate stock. Contact us for lead time.

What is ADAM10 Recombinant Rabbit Monoclonal Antibody [JM32-11] used for?

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.