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Product details

NeuroD1 Recombinant Rabbit Monoclonal Antibody [JM11-10]

Catalog number ET1703-73

Price for ET1703-73

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Size / count 100 µL

About this product

The basic helix-loop-helix (bHLH) proteins are transcription factors that are required for several aspects of development, including cell type determination, terminal differentiation and sex determination. The HLH domain is required for dimerization, while the basic region makes specific contacts with DNA. Members of the myogenic determination family, MyoD, myf5, myogenin and MRF4, all have bHLH domains. These proteins heterodimerize with members of the E protein family and initiate myogenesis. Neuro D has been identified as a bHLH transcription factor functioning in neurogenic differentiation. Neuro D is expressed transiently in a subset of neurons in the central and peripheral nervous systems at the time of their terminal differentiation into mature neurons. Moreover, ectopic expression of Neuro D in Xenopus embryos induces premature differentiation of neuronal precursors and Neuro D can convert presumptive epidermal cells into neurons.

Specifications

Catalog number
ET1703-73
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
atonal antibody basic helix loop helix transcription factor antibody BETA 2 antibody Beta cell E box transactivator 2 antibody BETA2 antibody BHF 1 antibody BHF1 antibody bHLHa3 antibody class A basic helix loop helix protein 3 antibody Class A basic helix-loop-helix protein 3 antibody MODY 6 antibody MODY6 antibody NDF1_HUMAN antibody NeuroD antibody NeuroD1 antibody Neurogenic differentiation 1 antibody Neurogenic differentiation factor 1 antibody neurogenic helix loop helix protein NEUROD antibody Neuronal differentiation 1 antibody
Abbreviation
NeuroD, NeuroD1, bHLHa3, NEUROD1
Swiss Prot
Q13562 Human, Q60867 Mouse, Q64289 Rat
Cellular Locus
Cytoplasm. Nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Human NeuroD1 aa 1-44 / 356.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IP, IHC-P, IHC-Fr
Positive Control
Rat brain tissue, mouse cerebellum tissue, rat cerebellum tissue, Human brain tissue lysate, SH-SY5Y cell lysate.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000 ;IP: 1:10-1:50 ;IHC-P: 1:200-1:500 ;IHC-Fr: 1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 40 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for NeuroD1 Recombinant Rabbit Monoclonal Antibody [JM11-10]?

The catalog number for NeuroD1 Recombinant Rabbit Monoclonal Antibody [JM11-10] is ET1703-73.

What sizes are available for NeuroD1 Recombinant Rabbit Monoclonal Antibody [JM11-10]?

NeuroD1 Recombinant Rabbit Monoclonal Antibody [JM11-10] is available in the following size(s): 100 µL.

Is NeuroD1 Recombinant Rabbit Monoclonal Antibody [JM11-10] in stock?

NeuroD1 Recombinant Rabbit Monoclonal Antibody [JM11-10] is currently made to order / not held in immediate stock. Contact us for lead time.

What is NeuroD1 Recombinant Rabbit Monoclonal Antibody [JM11-10] used for?

The basic helix-loop-helix (bHLH) proteins are transcription factors that are required for several aspects of development, including cell type determination, terminal differentiation and sex determination. The HLH domain is required for dimerization, while the basic region makes specific contacts wi

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

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