RPE65 Recombinant Rabbit Monoclonal Antibody [JM61-51]

Catalog number ET1703-82

Price for ET1703-82

Size / count 100 µL

About this product

The retinal pigment epithelium (RPE) is a monolayer simple epithelium in proximity to the outer surface of the retinal photoreceptor cells. Retinal pigment epithelium-specific protein (RPE65) is a 65kDa protein belonging to the beta-carotene dioxygenase family. This protein is important in 11-cis retinal production as well as in visual pigment regeneration. RPE65 is attached to the membrane by a lipid anchor when palmitoylated (membrane form) and soluble when unpalmitoylated. The soluble form of the protein binds vitamin A. Defects in RPE65 causes autosomal dominant retinitis pigmentosa and/or Leber congenital amaurosis type 2.

Specifications

Catalog number: ET1703-82
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: All-trans-retinyl-palmitate hydrolase antibody LCA 2 antibody LCA2 antibody Leber congenital amaurosis antibody mRPE 65 antibody mRPE65 antibody p63 antibody rd 12 antibody rd12 antibody Retinal pigment epithelium specific 61 kDa protein antibody Retinal pigment epithelium specific 65 kDa protein antibody Retinal pigment epithelium specific protein antibody Retinal pigment epithelium specific protein 65kDa antibody Retinal pigment epithelium-specific 65 kDa protein antibody Retinitis pigmentosa 20 antibody Retinoid isomerohydrolase antibody Retinol isomerase antibody RP 20 antibody RP20 antibody RPE 65 antibody RPE65 antibody RPE65_HUMAN antibody sRPE 65 antibody sRPE65 antibody
Abbreviation: RPE65
Swiss Prot: Q16518 Human, Q91ZQ5 Mouse, O70276 Rat
Cellular Locus: Cytoplasm. Cell membrane.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within Human RPE65 aa 441-484 / 533.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IP, IHC-P, IF-Tissue
Positive Control: Mouse eyeball tissue lysate, Rat eyeball tissue lysate, rat eyeball tissue, mouse eyeball tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:2,000 ;IP: 1:10-1:50 ;IHC-P: 1:1,000 ;IF-Tissue: 1:500
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 61 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for RPE65 Recombinant Rabbit Monoclonal Antibody [JM61-51]?

The catalog number for RPE65 Recombinant Rabbit Monoclonal Antibody [JM61-51] is ET1703-82.

What sizes are available for RPE65 Recombinant Rabbit Monoclonal Antibody [JM61-51]?

RPE65 Recombinant Rabbit Monoclonal Antibody [JM61-51] is available in the following size(s): 100 µL.

Is RPE65 Recombinant Rabbit Monoclonal Antibody [JM61-51] in stock?

RPE65 Recombinant Rabbit Monoclonal Antibody [JM61-51] is currently made to order / not held in immediate stock. Contact us for lead time.

What is RPE65 Recombinant Rabbit Monoclonal Antibody [JM61-51] used for?

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.