delta Sarcoglycan Recombinant Rabbit Monoclonal Antibody [JM61-10]

About this product

Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix. Defects in SGCD are the cause of limb-girdle muscular dystrophy type 2F (LGMD2F) [MIM:601287]. LGMD2F is an autosomal recessive disorder. Defects in SGCD are the cause of cardiomyopathy dilated type 1L (CMD1L) [MIM:606685]. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.

Specifications

Catalog number

ET1703-88

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

35 kDa dystrophin associated glycoprotein antibody 35 kDa dystrophin-associated glycoprotein antibody 35DAG antibody CMD1L antibody DAGD antibody Delta-sarcoglycan antibody Delta-SG antibody Dystrophin associated glycoprotein delta sarcoglycan antibody LGMD2F antibody MGC22567 antibody Placental delta sarcoglycan antibody Sarcoglycan delta (35 kDa dystrophin associated glycoprotein) antibody SG delta antibody SGCD antibody SGCD_HUMAN antibody SGCDP antibody SGD antibody

Abbreviation

Delta-SG, 35DAG, SGCD

Swiss Prot

Q92629 Human

Cellular Locus

Cytoskeleton, sarcolemma.

Host

Rabbit

Species Reactivity

Human

Immunogen

Synthetic peptide within Human delta Sarcoglycan aa 221-265 / 289.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IP, IHC-P

Positive Control

Human lung tissue lysate, human skeletal muscle tissue lysate, human stomach carcinoma tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:2,000 ;IHC-P: 1:50-1:200 ;IP: Use at an assay dependent concentration.

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

32 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes