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Product details

MIF Recombinant Rabbit Monoclonal Antibody [JM11-64]

Catalog number ET1703-89

Price for ET1703-89

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Size / count 100 µL

About this product

Macrophage migration inhibitory factor, known as MIF or glycosylation-inhibiting factor, is a secreted, homotrimeric, pro-inflammatory cytokine that modulates macrophage and T cell function and is an important regulator of host response to infection. MIF is expressed at sites of inflammation, which suggests that it plays a role in regulating macrophage function in host defense. MIF is produced by the pituitary gland and is found in monocytes, macrophages, differentiating immunological cells in the eye lens and brain, and fibroblasts. Elevated levels of MIF protein are detected in the plasma of patients with severe sepsis or septic shock, a condition where MIF influences endotoxic shock by enhancing the production of other inflammatory cytokines including tumor necrosis factor α (TNFα), interleukin-1 (IL-1) and interferon-γ (IFN-γ). MIF promotes the systemic inflammatory response by counter-regulating glucocorticoid-mediated inhibition of immune-cell activation and proinflammatory cytokine production. MIF may mediate tissue destruction through the induction of proteinases.

Specifications

Catalog number
ET1703-89
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
GIF antibody GLIF antibody Glycosylation inhibiting factor antibody Glycosylation-inhibiting factor antibody L-dopachrome isomerase antibody L-dopachrome tautomerase antibody Macrophage migration inhibitory factor (glycosylation-inhibiting factor) antibody Macrophage migration inhibitory factor antibody MIF antibody MIF protein antibody MIF_HUMAN antibody MMIF antibody Phenylpyruvate tautomerase antibody
Abbreviation
MIF, GIF
Swiss Prot
P14174 Human, P34884 Mouse, P30904 Rat
Cellular Locus
Secreted. Cytoplasm.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within human MIF aa 60-90.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IP, FC
Positive Control
Mouse brain tissue lysate, Jurkat cell lysate, Hela cell lysate, THP-1.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000 ;IP: 1:10-1:50 ;FC: 1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
12 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for MIF Recombinant Rabbit Monoclonal Antibody [JM11-64]?

The catalog number for MIF Recombinant Rabbit Monoclonal Antibody [JM11-64] is ET1703-89.

What sizes are available for MIF Recombinant Rabbit Monoclonal Antibody [JM11-64]?

MIF Recombinant Rabbit Monoclonal Antibody [JM11-64] is available in the following size(s): 100 µL.

Is MIF Recombinant Rabbit Monoclonal Antibody [JM11-64] in stock?

MIF Recombinant Rabbit Monoclonal Antibody [JM11-64] is currently made to order / not held in immediate stock. Contact us for lead time.

What is MIF Recombinant Rabbit Monoclonal Antibody [JM11-64] used for?

Macrophage migration inhibitory factor, known as MIF or glycosylation-inhibiting factor, is a secreted, homotrimeric, pro-inflammatory cytokine that modulates macrophage and T cell function and is an important regulator of host response to infection. MIF is expressed at sites of inflammation, which

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

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