Bid Recombinant Rabbit Monoclonal Antibody [JM11-14]

About this product

Members of the Bcl-2 family of proteins interact to regulate programmed cell death, or apoptosis. Various homodimers and heterodimers formed by proteins in this family can either promote or inhibit apoptosis. Bcl-2 blocks cell death following a variety of stimuli and confers a death-sparing effect on certain hematopoietic cell lines following growth factor withdrawal. Additional apoptotic inhibitors in this family include A1, Bag-1, Bcl-w, Bcl-x and Mcl-1. Pro-apoptotic members of this family include Bax, Bad, Bak, Bik (NBK) and BID. BID contains a BH3 domain which allows it to dimerize with and counter the death repressor effects of Bcl-2. BID has also been shown to heterodimerize with Bcl-x and the death agonist Bax. BID is localized predominantly in the cytosol and is also present in membrane fractions. It is highly expressed in kidney and can also be detected in brain, spleen, liver, testis and lung.

Specifications

Catalog number

ET1703-92

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

Apoptic death agonist antibody Apoptotic death agonist BID antibody BH3 interacting domain death agonist antibody BH3 interacting domain death agonist p11 antibody BH3 interacting domain death agonist p13 antibody BH3 interacting domain death agonist p15 antibody BH3-interacting domain death agonist p11 antibody BID antibody BID isoform ES (1b) antibody BID isoform L (2) antibody BID isoform Si6 antibody BID_HUMAN antibody Desmocollin type 4 antibody FP497 antibody Human BID coding sequence antibody MGC15319 antibody MGC42355 antibody p11 BID antibody p13 BID antibody p15 BID antibody p22 BID antibody

Abbreviation

BID

Swiss Prot

P55957 Human

Cellular Locus

Cytoplasm. Mitochondrion membrane.

Host

Rabbit

Species Reactivity

Human

Immunogen

Synthetic peptide within Human Bid aa 40-72 / 195.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IHC-P, FC, IP

Positive Control

Jurkat cells lysates, Hela, PC-3M, SW480, human tonsil tissue, human lung tissue, human liver cancer tissue, human colon cancer tissue, human spleen tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:1,000 ;IF-Cell: 1:50-1:200 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100 ;IP: 1:10-1:50

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 22 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes