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Product details

CD18 Recombinant Rabbit Monoclonal Antibody [JM71-31]

Catalog number ET1703-94

Price for ET1703-94

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Size / count 100 µL

About this product

Integrins are heterodimers composed of noncovalently associated transmembrane a and b subunits. The 16 a and 8 b subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, Collagen and Vitronectin. Certain integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.

Specifications

Catalog number
ET1703-94
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
95 subunit beta antibody Beta 2 (antigen CD18 (p95) antibody CD 18 antibody CD18 antibody Cell surface adhesion glycoprotein LFA 1/CR3/P150,959 beta subunit precursor) antibody Cell surface adhesion glycoproteins LFA 1/CR3/p150,95 subunit beta antibody Cell surface adhesion glycoproteins LFA-1/CR3/p150 antibody Complement component 3 receptor 3 and 4 subunit antibody Complement receptor C3 beta subunit antibody Complement receptor C3 subunit beta antibody Integrin beta 2 antibody Integrin beta chain beta 2 antibody Integrin beta-2 (ITGB2) antibody Integrin beta-2 antibody Integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) antibody ITB2_HUMAN antibody ITGB2 antibody LAD antibody LCAMB antibody Leukocyte associated antigens CD18/11A, CD18/11B, CD18/11C antibody Leukocyte cell adhesion molecule CD18 antibody LFA 1 antibody LFA1 antibody Lymphocyte function associated antigen 1 (LFA1) antibody Lymphocyte function associated antigen 1 antibody MAC 1 antibody MAC1 antibody Macrophage antigen 1 (mac1) beta antibody MF17 antibody MFI7 antibody OTTHUMP00000115278 antibody OTTHUMP00000115279 antibody OTTHUMP00000115280 antibody OTTHUMP00000115281 antibody OTTHUMP00000115282 antibody
Abbreviation
ITGB2
Swiss Prot
P05107 Human
Cellular Locus
Membrane.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within Human CD18 aa 103-146 / 769.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IP
Positive Control
Jurkat cell lysates.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000 ;IP: 1:10-1:50
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 85 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for CD18 Recombinant Rabbit Monoclonal Antibody [JM71-31]?

The catalog number for CD18 Recombinant Rabbit Monoclonal Antibody [JM71-31] is ET1703-94.

What sizes are available for CD18 Recombinant Rabbit Monoclonal Antibody [JM71-31]?

CD18 Recombinant Rabbit Monoclonal Antibody [JM71-31] is available in the following size(s): 100 µL.

Is CD18 Recombinant Rabbit Monoclonal Antibody [JM71-31] in stock?

CD18 Recombinant Rabbit Monoclonal Antibody [JM71-31] is currently made to order / not held in immediate stock. Contact us for lead time.

What is CD18 Recombinant Rabbit Monoclonal Antibody [JM71-31] used for?

Integrins are heterodimers composed of noncovalently associated transmembrane a and b subunits. The 16 a and 8 b subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, Collagen

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

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