Axin2 Recombinant Rabbit Monoclonal Antibody [JM11-30] — image 1 of 3

Product details

Axin2 Recombinant Rabbit Monoclonal Antibody [JM11-30]

Catalog number ET1703-96

Price for ET1703-96

Size / count 100 µL

About this product

b-catenin is a component of both the cadherin cell adhesion system and the Wnt signaling pathway. Wnt signaling increases the amount of b-catenin, by preventing its ubiquitination and degradation, allowing its direct interaction with transcription factors of the lymphoid enhancer factor-T cell factor family and modulation of gene expression. Axin is involved in the degradation of b-catenin by acting as a scaffold to form a complex between b-catenin, adenomatous polyposis coli (APC) and GSK-3b. APC, which is phosphorylated by GSK-3b, induces degradation of b-catenin, thus inhibiting Wnt signal transduction. Conductin is 45% identical to axin and appears to play a similar role to axin in the Wnt signaling pathway.

Specifications

Catalog number: ET1703-96
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: Axil antibody Axin like protein antibody Axin-2 antibody Axin-like protein antibody Axin2 antibody AXIN2_HUMAN antibody Axis inhibition protein 2 antibody Conductin antibody DKFZp781B0869 antibody MGC10366 antibody MGC126582 antibody
Abbreviation: Axil, AXIN2
Swiss Prot: Q9Y2T1 Human, O88566 Mouse, O70240 Rat
Cellular Locus: Cytoplasm.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within Human Axin2 aa 55-93 / 843.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P
Positive Control: SW480 cell lysate, PC-12 cell lysate, NIH/3T3 cell lysate, human colon cancer tissue, mouse colon tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:2,000 ;IHC-P: 1:50
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 94 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Axin2 Recombinant Rabbit Monoclonal Antibody [JM11-30]?

The catalog number for Axin2 Recombinant Rabbit Monoclonal Antibody [JM11-30] is ET1703-96.

What sizes are available for Axin2 Recombinant Rabbit Monoclonal Antibody [JM11-30]?

Axin2 Recombinant Rabbit Monoclonal Antibody [JM11-30] is available in the following size(s): 100 µL.

Is Axin2 Recombinant Rabbit Monoclonal Antibody [JM11-30] in stock?

Axin2 Recombinant Rabbit Monoclonal Antibody [JM11-30] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Axin2 Recombinant Rabbit Monoclonal Antibody [JM11-30] used for?

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.