Mre11 Recombinant Rabbit Monoclonal Antibody [JM11-18] — image 1 of 3

Product details

Mre11 Recombinant Rabbit Monoclonal Antibody [JM11-18]

Catalog number ET1703-99

Price for ET1703-99

Size / count 100 µL

About this product

Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11. RAD50 may be required to bind DNA ends and hold them in close proximity. This could facilitate searches for short or long regions of sequence homology in the recombining DNA templates, and may also stimulate the activity of DNA ligases and/or restrict the nuclease activity of MRE11 to prevent nucleolytic degradation past a given point. The complex may also be required for DNA damage signaling via activation of the ATM kinase. In telomeres the MRN complex may modulate t-loop formation.

Specifications

Catalog number: ET1703-99
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: AT like disease antibody Ataxia telangiectasia disorder like antibody ATLD antibody DNA recombination and repair protein antibody Double strand break repair protein MRE11A antibody Double-strand break repair protein MRE11A antibody endo/exonuclease Mre11 antibody HNGS1 antibody meiotic recombination (S. cerevisiae) 11 homolog A antibody Meiotic recombination 11 homolog 1 antibody meiotic recombination 11 homolog A (S. cerevisiae) antibody Meiotic recombination 11 homolog A antibody MmMRE11A antibody Mre 11 antibody MRE 11a antibody MRE 11b antibody MRE11 homolog 1 antibody MRE11 homolog A antibody MRE11 meiotic recombination 11 homolog A (S. cerevisiae) antibody MRE11 meiotic recombination 11 homolog A antibody MRE11_HUMAN antibody MRE11A antibody MRE11b antibody OTTHUMP00000236830 antibody OTTHUMP00000236831 antibody OTTHUMP00000236832 antibody OTTHUMP00000236833 antibody
Abbreviation: MRE11 homolog 1, MRE11 homolog A, MRE11
Swiss Prot: P49959 Human, Q61216 Mouse, Q9JIM0 Rat
Cellular Locus: Nucleus.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within Human Mre11 aa 465-498 / 708.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P
Positive Control: HeLa cell lysate, 293T cell lysate, human breast cancer tissue, human stomach cancer tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000 ;IHC-P: 1:50-1:200
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 81 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Mre11 Recombinant Rabbit Monoclonal Antibody [JM11-18]?

The catalog number for Mre11 Recombinant Rabbit Monoclonal Antibody [JM11-18] is ET1703-99.

What sizes are available for Mre11 Recombinant Rabbit Monoclonal Antibody [JM11-18]?

Mre11 Recombinant Rabbit Monoclonal Antibody [JM11-18] is available in the following size(s): 100 µL.

Is Mre11 Recombinant Rabbit Monoclonal Antibody [JM11-18] in stock?

Mre11 Recombinant Rabbit Monoclonal Antibody [JM11-18] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Mre11 Recombinant Rabbit Monoclonal Antibody [JM11-18] used for?

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.