MUC2 Recombinant Rabbit Monoclonal Antibody [JA10-92]

About this product

The mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs) encoded by 60 base pairs (Mucin 1), 69 base pairs (Mucin 2) and 51 base pairs (Mucin 3). The number of repeats is highly polymorphic and varies among different alleles. Mucin 1 proteins are expressed as type I membrane proteins in addition to secreted forms. Mucin 1 is aberrantly expressed in epithelial tumors including breast carcinomas. Mucin 2 coats the epithelia of the intestines and airways and is associated with colonic tumors. Mucin 3 is a major com-ponent of various mucus gels and is broadly expressed in normal and tumor cells.

Specifications

Catalog number

ET1704-06

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

Yes

CAS Number

9000-83-3

Product Name Alternative

Intestinal mucin 2 antibody Intestinal mucin-2 antibody MLP antibody MUC 2 antibody MUC-2 antibody Muc2 antibody MUC2_HUMAN antibody Mucin 2 antibody Mucin 2 intestinal antibody Mucin 2 intestinal/tracheal antibody Mucin 2 oligomeric mucus/gel forming antibody Mucin 2 precursor antibody Mucin 2 tracheal antibody Mucin like protein antibody Mucin-2 antibody Mucin2 antibody SMUC antibody

Abbreviation

MUC-2, MUC2

Swiss Prot

Q02817 Human, Q62635 Rat

Cellular Locus

Secreted.

Host

Rabbit

Species Reactivity

Human

Immunogen

Synthetic peptide within Human MUC2 aa 5100-5149 / 5179.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IHC-P, FC

Positive Control

SHSY-5Y cell lysate, SKBR3 cell lysate, Hela, HepG2, SW480, human colon tissue, human small intestine tissue, human colon tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:1,000 ;IF-Cell: 1:100-1:500 ;IF-Tissue: 1:100-1:500 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

540 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes