TLR7 Recombinant Rabbit Monoclonal Antibody [JA93-11]

Catalog number ET1704-11

Price for ET1704-11

Size / count 100 µL

About this product

The Toll-like Receptors (TLR) are a family of human receptors that share homology with the Drosophila Toll Receptors, which are involved in mediating dorsoventral polarization in developing Drosophila embryos and participate in host immunity. The TLR family members are characterized by a highly conserved Toll homology (TH) domain, which is essential for Toll-induced signal transductions. TLRs are type I transmembrane receptors that contain an extracellular domain consisting of several leucine-rich regions and a single cytoplasmic Toll/IL-1R like domain. Three TLR family members, TLR7, TLR8 and TLR9, belong to a subfamily of TLRs which are differentially expressed. TLR7 is expressed in lung, placenta and spleen. TLR8 is expressed in lung and peripheral blood leukocytes, and TLR9 is predominantly expressed in spleen, lymph nodes, bone marrow and peripheral blood leukocytes. TLR7, TLR8 and TLR9 stimulate the NFκB signaling pathway, suggesting that they play a role in the immune response.

Specifications

Catalog number: ET1704-11
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: PRO285 antibody TLR 7 antibody Tlr7 antibody TLR7_HUMAN antibody Toll like receptor 7 antibody Toll-like receptor 7 antibody UNQ248 antibody
Abbreviation: TLR7
Swiss Prot: Q9NYK1 Human
Cellular Locus: Endoplasmic reticulum membrane, Endosome, Lysosome, Cytoplasmic vesicle, phagosome.
Host: Rabbit
Species Reactivity: Human
Immunogen: Synthetic peptide within Human TLR7 aa 1000-1049 / 1049.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB
Positive Control: Jurkat cell lysate, Daudi cell lysate.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 121 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for TLR7 Recombinant Rabbit Monoclonal Antibody [JA93-11]?

The catalog number for TLR7 Recombinant Rabbit Monoclonal Antibody [JA93-11] is ET1704-11.

What sizes are available for TLR7 Recombinant Rabbit Monoclonal Antibody [JA93-11]?

TLR7 Recombinant Rabbit Monoclonal Antibody [JA93-11] is available in the following size(s): 100 µL.

Is TLR7 Recombinant Rabbit Monoclonal Antibody [JA93-11] in stock?

TLR7 Recombinant Rabbit Monoclonal Antibody [JA93-11] is currently made to order / not held in immediate stock. Contact us for lead time.

What is TLR7 Recombinant Rabbit Monoclonal Antibody [JA93-11] used for?

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.