Tyrosinase Recombinant Rabbit Monoclonal Antibody [JA52-11] — image 1 of 3

Product details

Tyrosinase Recombinant Rabbit Monoclonal Antibody [JA52-11]

Catalog number ET1704-18

Price for ET1704-18

Size / count 100 µL

About this product

This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone. Defects in TYR are the cause of albinism oculocutaneous type 1B (OCA1B) [MIM:606952]; also known as albinism yellow mutant type. An autosomal recessive disorder in which the biosynthesis of melanin pigment is reduced in skin, hair, and eyes. It is characterized by partial lack of tyrosinase activity.

Specifications

Catalog number: ET1704-18
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: ATN antibody CMM8 antibody LB24 AB antibody LB24-AB antibody Monophenol monooxygenase antibody OCA1 antibody OCA1A antibody OCAIA antibody Oculocutaneous albinism IA antibody SHEP3 antibody SK29 AB antibody SK29-AB antibody Tumor rejection antigen AB antibody TYR antibody TYRO_HUMAN antibody tyrosinase (oculocutaneous albinism IA) antibody Tyrosinase antibody
Abbreviation: TYR
Swiss Prot: P14679 Human, P11344 Mouse
Cellular Locus: Melanosome membrane, Melanosome.
Host: Rabbit
Species Reactivity: Human, Mouse
Immunogen: Recombinant protein within Human Tyrosinase aa 1-340 / 529.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell, IF-Tissue, IHC-P
Positive Control: B16F1 cell lysates, A431, B16F1, MCF-7, human liver tissue, human stomach carcinoma tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:2,000;IF-Cell: 1:100-1:500;IF-Tissue: 1:100-1:500;IHC-P: 1:50-1:200
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 60 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Tyrosinase Recombinant Rabbit Monoclonal Antibody [JA52-11]?

The catalog number for Tyrosinase Recombinant Rabbit Monoclonal Antibody [JA52-11] is ET1704-18.

What sizes are available for Tyrosinase Recombinant Rabbit Monoclonal Antibody [JA52-11]?

Tyrosinase Recombinant Rabbit Monoclonal Antibody [JA52-11] is available in the following size(s): 100 µL.

Is Tyrosinase Recombinant Rabbit Monoclonal Antibody [JA52-11] in stock?

Tyrosinase Recombinant Rabbit Monoclonal Antibody [JA52-11] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Tyrosinase Recombinant Rabbit Monoclonal Antibody [JA52-11] used for?

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.