Hepcidin Recombinant Rabbit Monoclonal Antibody [JA11-27] — image 1 of 3

Product details

Hepcidin Recombinant Rabbit Monoclonal Antibody [JA11-27]

Catalog number ET1704-22

Price for ET1704-22

Size / count 100 µL

About this product

Hepcidin, also known as HAMP, HEPC, LEAP1 or HFE2B, is an 84 amino acid secreted protein that regulates iron-related signaling events. Highly expressed in liver with lower expression in heart, brain, lung, prostate and thyroid, hepcidin is thought to maintain iron homeostasis and, in conjunction with the HFE protein (a protein that is defective in hereditary hemochromatosis), may mediate both iron storage in macrophages and intestinal iron absorption. Additionally, hepcidin has strong antimicrobial activity against gram-positive and gram-negative bacteria, as well as certain yeast strains, suggesting that hepcidin may play a crucial role in staving off bacterial infections. Defects in the gene encoding hepcidin are the cause of hemochromatosis type 2B (also known as juvenile hemochromatosis), an early-onset autosomal recessive disorder that results in severe iron overload and is characterized by hepatic fibrosis, hypogonadotrophic hypogonadism and cardiomyopathy.

Specifications

Catalog number: ET1704-22
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: Hamp antibody HEPC antibody HEPC_HUMAN antibody Hepc20 antibody Hepc25 antibody Hepcidin-20 antibody HFE2B antibody LEAP-1 antibody LEAP1 antibody Liver-expressed antimicrobial peptide 1 antibody PLTR antibody Putative liver tumor regressor antibody
Abbreviation: LEAP-1, PLTR, Hepc25, Hepc20, HAMP
Swiss Prot: P81172 Human
Cellular Locus: Secreted.
Host: Rabbit
Species Reactivity: Human, Rat
Immunogen: Recombinant protein within Hepcidin aa 1-84 / 84.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P
Positive Control: Human liver tissue, rat heart tissue, rat brain tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:1,000 ;IHC-P: 1:50-1:200
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 9 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Hepcidin Recombinant Rabbit Monoclonal Antibody [JA11-27]?

The catalog number for Hepcidin Recombinant Rabbit Monoclonal Antibody [JA11-27] is ET1704-22.

What sizes are available for Hepcidin Recombinant Rabbit Monoclonal Antibody [JA11-27]?

Hepcidin Recombinant Rabbit Monoclonal Antibody [JA11-27] is available in the following size(s): 100 µL.

Is Hepcidin Recombinant Rabbit Monoclonal Antibody [JA11-27] in stock?

Hepcidin Recombinant Rabbit Monoclonal Antibody [JA11-27] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Hepcidin Recombinant Rabbit Monoclonal Antibody [JA11-27] used for?

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.