FAP Recombinant Rabbit Monoclonal Antibody [JA56-11] — image 1 of 2

Product details

FAP Recombinant Rabbit Monoclonal Antibody [JA56-11]

Catalog number ET1704-23

Discontinued

Price for ET1704-23

Size / count 100 µL

This variant is discontinued and cannot be added to your cart.

About this product

FAP (fibroblast activation protein) is a cell surface glycoprotein and serine protease that is expressed primarily in fetal mesenchymal tissues and epithelial cancer fibroblasts. In cancer, FAP functions to promote cellular proliferation. In embryonic development, FAP functions to remodel developing tissues. FAP acts as an integral membrane gelatinase composed of N-glycosylated proteolytically inactive subunits. FAP expression on chondrocyte membranes is upregulated by the combination of the cytokines IL-1 and OSM and has been shown to increase in osteoarthritic patients. This expression is co-localized with MMP-1and MMP-13 as well as CD44 (variants v3 and v7/8). Mice that lack all copies of the FAP gene have been found to be fertile and to have developmental defects or change in cancer susceptibility.

Specifications

Catalog number: ET1704-23
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
CAS Number: 9000-83-3
Product Name Alternative: 170 kDa melanoma membrane bound gelatinase antibody 170 kDa melanoma membrane-bound gelatinase antibody DPPIV antibody FAP antibody FAPA antibody Fibroblast activation protein alpha antibody Integral membrane serine protease antibody SEPR_HUMAN antibody Seprase antibody
Abbreviation: FAPalpha, SIMP, Seprase, FAP
Swiss Prot: Q12884 Human, P97321 Mouse, Q8R492 Rat
Cellular Locus: Cell membrane. Cell surface.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within Human FAP1 aa 1-160 / 760.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P, mIHC, IHC-Fr
Positive Control: U-87 MG cell lysates, human pancreatic carcinoma, human colon cancer tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000 ;IHC-P: 1:1,000 ;mIHC: 1:3,000 ;IHC-Fr: 1:200
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 88 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for FAP Recombinant Rabbit Monoclonal Antibody [JA56-11]?

The catalog number for FAP Recombinant Rabbit Monoclonal Antibody [JA56-11] is ET1704-23.

Is FAP Recombinant Rabbit Monoclonal Antibody [JA56-11] in stock?

FAP Recombinant Rabbit Monoclonal Antibody [JA56-11] is currently made to order / not held in immediate stock. Contact us for lead time.

What is FAP Recombinant Rabbit Monoclonal Antibody [JA56-11] used for?

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.