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![IL-4 Recombinant Rabbit Monoclonal Antibody [JA86-10] — image 1 of 3](https://cdn.genprice.uk/products/992/68dd1c8b061270361ea8169f/imageurl/et1704-28.webp)
Product details
Catalog number ET1704-28
Price for ET1704-28
Size / count 100 µL
Interleukin-4 (IL-4), also designated B cell stimulatory factor-1, is a glycosylated cytokine secreted by activated T lymphocytes, basophils and mast cells. The secreted IL-4 protein promotes the growth and differentiation of cells that participate in immune defense by favoring such events as the expansion of the Th2 lineage relative to Th1 cells. These T helper cell subsets are defined by their pattern of cytokine secretion: Th1 cells secrete IL-2, TNFβ and IFN-γ, while Th2 cells secrete IL-4, IL-5 and IL-10. Another key immunological function of IL-4 is to induce immunoglobulin class switching. IL-4 has been shown to induce the production of IgE and enhance IgG4 secretion by B cells, but suppress the production of IgM, IgA, IgG1, IgG2, and IgG3. It has been determined that Stat6 is rapidly tyrosine phosphorylated following stimulation of IL-3 or IL-4, but is not detectably phosphorylated following stimulation with IL-2, IL-12 or erythropoietin.
The catalog number for IL-4 Recombinant Rabbit Monoclonal Antibody [JA86-10] is ET1704-28.
IL-4 Recombinant Rabbit Monoclonal Antibody [JA86-10] is available in the following size(s): 100 µL.
IL-4 Recombinant Rabbit Monoclonal Antibody [JA86-10] is currently made to order / not held in immediate stock. Contact us for lead time.
Interleukin-4 (IL-4), also designated B cell stimulatory factor-1, is a glycosylated cytokine secreted by activated T lymphocytes, basophils and mast cells. The secreted IL-4 protein promotes the growth and differentiation of cells that participate in immune defense by favoring such events as the ex
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