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Product details

Integrin alpha 4 Recombinant Rabbit Monoclonal Antibody [JA09-36]

Catalog number ET1704-31

Price for ET1704-31

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Size / count 100 µL

About this product

Integrins are heterodimers composed of noncovalently associated transmembrane α and β subunits. The 16 α and 8 β subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including fibronectin, collagen and vitronectin. Certain integrins can also bind to soluble ligands such as fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.

Specifications

Catalog number
ET1704-31
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
269C wild type antibody Antigen CD49D, alpha 4 subunit of VLA 4 receptor antibody CD49 antigen like family member D antibody CD49 antigen-like family member D antibody CD49d antibody IA4 antibody Integrin alpha 4 antibody Integrin alpha 4 subunit antibody Integrin alpha IV antibody Integrin alpha-4 antibody Integrin alpha-IV antibody Integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA 4 receptor) antibody ITA4_HUMAN antibody ITGA4 antibody MGC90518 antibody OTTHUMP00000205320 antibody Very late activation protein 4 receptor, alpha 4 subunit antibody VLA 4 subunit alpha antibody VLA-4 subunit alpha antibody VLA4 antibody
Abbreviation
ITGA4, CD49d
Swiss Prot
P13612 Human, Q00651 Mouse,
Cellular Locus
Membrane.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Human Integrin alpha 4 aa 983-1032 / 1032.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
Jurkat cell lysate, mouse spleen tissue lysate, rat spleen tissue lysate, RAW264.7 cell lysate, human tonsil tissue, human spleen tissue, Jurkat.
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IHC-P: 1:50-1:200 ;FC: 1:10-1:50
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 115 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Integrin alpha 4 Recombinant Rabbit Monoclonal Antibody [JA09-36]?

The catalog number for Integrin alpha 4 Recombinant Rabbit Monoclonal Antibody [JA09-36] is ET1704-31.

What sizes are available for Integrin alpha 4 Recombinant Rabbit Monoclonal Antibody [JA09-36]?

Integrin alpha 4 Recombinant Rabbit Monoclonal Antibody [JA09-36] is available in the following size(s): 100 µL.

Is Integrin alpha 4 Recombinant Rabbit Monoclonal Antibody [JA09-36] in stock?

Integrin alpha 4 Recombinant Rabbit Monoclonal Antibody [JA09-36] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Integrin alpha 4 Recombinant Rabbit Monoclonal Antibody [JA09-36] used for?

Integrins are heterodimers composed of noncovalently associated transmembrane α and β subunits. The 16 α and 8 β subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including fibronectin, collagen

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

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