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Product details

Noxa Recombinant Rabbit Monoclonal Antibody [JA30-03]

Catalog number ET1704-35

Price for ET1704-35

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Size / count 100 µL

About this product

Members of the Bcl-2 family of proteins interact to regulate programmed cell death (apoptosis) under a broad range of physiological conditions. Bcl-2, Bcl-xL, and several related proteins inhibit apoptosis, whereas other members of the Bcl-2 family, such as Bax and Bak, enhance cell death. NOXA, a pro-apoptotic member of the Bcl-2 family, contains the Bcl-2 homology 3 (BH3) region, but does not contain other BH domains. Murine cells constitutively express NOXA mRNA in small amounts in various organs; X-ray irradiation increases NOXA mRNA and protein expression levels. In human cells, NOXA, alternatively designated PMA-induced protein 1 or APR, displays high expression in the adult T cell leukemia cell line IKD, where it may function as an immediate-early-response gene. The NOXA protein selectively localizes to mitochondria.

Specifications

Catalog number
ET1704-35
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
Adult T cell leukemia derived PMA responsive antibody APR antibody APR_HUMAN antibody ATL-derived antibody Immediate early response protein APR antibody Immediate-early-response protein APR antibody NOXA antibody Phorbol 12 myristate 13 acetate induced protein 1 antibody Phorbol-12-myristate-13-acetate-induced protein 1 antibody PMA induced protein 1 antibody PMA-induced protein 1 antibody PMA-responsive gene antibody Pmaip1 antibody Protein Noxa antibody
Abbreviation
PMA-induced protein 1, PMAIP1, NOXA
Swiss Prot
Q13794 Human, Q9JM54 Mouse, Q5U777 Rat
Cellular Locus
Mitochondrion.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Human Noxa aa 5-54 / 54.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P
Positive Control
Human spleen tissue, human liver tissue, Jurkat, mouse lung tissue, rat lung tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500 ;IHC-P: 1:8,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 6 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Noxa Recombinant Rabbit Monoclonal Antibody [JA30-03]?

The catalog number for Noxa Recombinant Rabbit Monoclonal Antibody [JA30-03] is ET1704-35.

What sizes are available for Noxa Recombinant Rabbit Monoclonal Antibody [JA30-03]?

Noxa Recombinant Rabbit Monoclonal Antibody [JA30-03] is available in the following size(s): 100 µL.

Is Noxa Recombinant Rabbit Monoclonal Antibody [JA30-03] in stock?

Noxa Recombinant Rabbit Monoclonal Antibody [JA30-03] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Noxa Recombinant Rabbit Monoclonal Antibody [JA30-03] used for?

Members of the Bcl-2 family of proteins interact to regulate programmed cell death (apoptosis) under a broad range of physiological conditions. Bcl-2, Bcl-xL, and several related proteins inhibit apoptosis, whereas other members of the Bcl-2 family, such as Bax and Bak, enhance cell death. NOXA, a p

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

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