Profilin 1 Recombinant Rabbit Monoclonal Antibody [JA30-13] — image 1 of 3

Product details

Profilin 1 Recombinant Rabbit Monoclonal Antibody [JA30-13]

Catalog number ET1704-42

Price for ET1704-42

Size / count 100 µL

About this product

Profilins regulate Actin polymerization by binding to and sequestering the Actin monomer. Profilins act as a nucleotide exchange factor that charges Actin with ATP after binding the Actin monomer through a 1:1 stoichiometric relationship. Human Profilin-1 and Profilin-2 are encoded by two separate genes mapping to chromosomes 17p13.2 and 3q25.1, respectively. Both Profilin-1 and Profilin-2 are abundantly expressed in kidney. Profilin-1 is highly expressed in lung, liver, placenta and kidney while Profilin-2 is highly expressed in brain and skeletal muscle. In axonal and dendritic processes of mouse brain, Profilins co-localize with dynamin I and synapsin. Profilin may play a role in mediating cell adhesion. The overexpression of Profilin in endothelial cells results in increased adhesion to Fibronectin. In food allergy, plant Profilin is considered a pan-allergen. Case studies indicate individuals with allergies to various foods including celery, carrots, zucchini and peanuts are actually sensitive to the Profilin proteins in these foods.

Specifications

Catalog number: ET1704-42
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: Actin binding protein antibody ALS18 antibody Epididymis tissue protein Li 184a antibody OTTHUMP00000125244 antibody PFN 1 antibody Pfn antibody PFN1 antibody PROF1_HUMAN antibody Profilin I antibody Profilin-1 antibody Profilin1 antibody ProfilinI antibody
Abbreviation: PFN1
Swiss Prot: P07737 Human, P62962 Mouse, P62963 Rat
Cellular Locus: Cytoskeleton.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within Human Profilin 1 aa 91-140 / 140.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell, IHC-P, FC
Positive Control: A549 cell lysate, Hela cell lysates, A431 cell lysate, A549, Hela, HepG2, human kidney tissue, mouse colon tissue, mouse kidney tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:2,000 ;IF-Cell: 1:50-1:200 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 15 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Profilin 1 Recombinant Rabbit Monoclonal Antibody [JA30-13]?

The catalog number for Profilin 1 Recombinant Rabbit Monoclonal Antibody [JA30-13] is ET1704-42.

What sizes are available for Profilin 1 Recombinant Rabbit Monoclonal Antibody [JA30-13]?

Profilin 1 Recombinant Rabbit Monoclonal Antibody [JA30-13] is available in the following size(s): 100 µL.

Is Profilin 1 Recombinant Rabbit Monoclonal Antibody [JA30-13] in stock?

Profilin 1 Recombinant Rabbit Monoclonal Antibody [JA30-13] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Profilin 1 Recombinant Rabbit Monoclonal Antibody [JA30-13] used for?

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.