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Product details

GDNF Recombinant Rabbit Monoclonal Antibody [JA93-10]

Catalog number ET1704-46

Price for ET1704-46

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Size / count 100 µL

About this product

Glial cell line-derived neurotrophic factor (GDNF) has been identified as a potent neurotrophic factor that enhances survival of midbrain dopaminergic neurons. GDNF is a glycosylated, disulfide-bonded homodimer and is a distantly related member of the TGFβ superfamily of growth regulatory ligands. GDNF contains the seven conserved cysteine residues in the same relative spacing characteristic of all members of the TGFβ superfamily. In embryonic midbrain cultures, GDNF promotes the survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. On the basis of these findings, it has been suggested that GDNF may have utility in the treatment of Parkinson's disease, which is marked by progressive degeneration of midbrain dopaminergic neurons.

Specifications

Catalog number
ET1704-46
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
Astrocyte derived trophic factor antibody Astrocyte derived trophic factor 1 antibody Astrocyte-derived trophic factor antibody ATF 1 antibody ATF 2 antibody Atf antibody ATF1 antibody ATF2 antibody gdnf antibody GDNF_HUMAN antibody Glial cell derived neurotrophic factor antibody Glial Cell Line Derived Neurotrophic Factor antibody Glial cell line-derived neurotrophic factor antibody Glial derived neurotrophic factor antibody HFB1 GDNF antibody hGDNF antibody HSCR3 antibody
Abbreviation
hGDNF, ATF, GDNF
Swiss Prot
P39905 Human, P48540 Mouse, Q07731 Rat
Cellular Locus
Secreted.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within human GDNF aa 51-100/211.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, FC
Positive Control
HepG2 cell lysates, SH-SY5Y.
Concentration
1 mg/mL
Dilution
WB: 1:500 ;FC: 1:50-1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
24 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for GDNF Recombinant Rabbit Monoclonal Antibody [JA93-10]?

The catalog number for GDNF Recombinant Rabbit Monoclonal Antibody [JA93-10] is ET1704-46.

What sizes are available for GDNF Recombinant Rabbit Monoclonal Antibody [JA93-10]?

GDNF Recombinant Rabbit Monoclonal Antibody [JA93-10] is available in the following size(s): 100 µL.

Is GDNF Recombinant Rabbit Monoclonal Antibody [JA93-10] in stock?

GDNF Recombinant Rabbit Monoclonal Antibody [JA93-10] is currently made to order / not held in immediate stock. Contact us for lead time.

What is GDNF Recombinant Rabbit Monoclonal Antibody [JA93-10] used for?

Glial cell line-derived neurotrophic factor (GDNF) has been identified as a potent neurotrophic factor that enhances survival of midbrain dopaminergic neurons. GDNF is a glycosylated, disulfide-bonded homodimer and is a distantly related member of the TGFβ superfamily of growth regulatory ligands. G

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

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