Annexin A2 Recombinant Rabbit Monoclonal Antibody [JA42-30]

About this product

The annexin family of calcium-binding proteins is composed of at least ten mammalian genes and is characterized by a conserved core domain which binds phospholipids in a Ca2+-dependent manner and a unique amino-terminal region which may confer binding specificity. The interaction between these proteins and biological membranes has led to the hypothesis that they are involved in cellular trafficking processes such as endocytosis, exocytosis and cellular adhesion. Annexin I, alternatively referred to as lipocortin, has been implicated as a mediator of the anti-inflammatory response produced by glucocorticoids and as an inhibitor of cPLA2, a potent mediator of inflammation. Annexin II, also called p36, exists as a monomer or as a heterotetramer, complexed with the S-100-related protein p11. This complex is termed calpactin I. In the tetrameric form, Annexin II is an efficient substrate of PKC family and Src pp60.

Specifications

Catalog number

ET1704-49

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

Annexin A2 antibody Annexin II antibody Annexin II, heavy chain antibody Annexin-2 antibody ANX 2 antibody ANX2 antibody ANX2L4 antibody ANXA2 antibody ANXA2_HUMAN antibody arylsulfatase B antibody CAL1H antibody Calpactin I heavy chain antibody calpactin I heavy polypeptide (p36) antibody Calpactin I heavy polypeptide antibody Calpactin-1 heavy chain antibody chromobindin 8 antibody Chromobindin-8 antibody Epididymis secretory protein Li 270 antibody HEL S 270 antibody LIP2 antibody Lipocortin II antibody LPC2 antibody LPC2D antibody p36 antibody P36 protein antibody PAP-IV antibody Placental anticoagulant protein IV antibody Protein I antibody

Abbreviation

PAP-IV, ANXA2, ANX2, ANX2L4, CAL1H, LPC2D

Swiss Prot

P07355 Human, P07356 Mouse, Q07936 Rat

Cellular Locus

Basement membrane. Melanosome.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within Human Annexin A2 aa 26-75 / 339.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P, IF-Cell, IF-Tissue, FC

Positive Control

A549 cell lysate, HeLa cell lysate, K-562 cell lysate, 293T cell lysate, NIH/3T3 cell lysate, RAW264.7 cell lysate, C6 cell lysate, PC-12 cell lysate, Hela, human liver tissue, human colon carcinoma tissue, human prostate tissue, K562.

Concentration

1 mg/mL

Dilution

WB: 1:1,000 ;IHC-P: 1:50-1:200 ;IF-Cell:1:100-1:200 ;IF-Tissue:1:100-1:200 ;FC:1:50-1:200

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 39 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes