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Product details

CHD4 Recombinant Rabbit Monoclonal Antibody [JA33-40]

Catalog number ET1704-53

Price for ET1704-53

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Size / count 100 µL

About this product

In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Chromatin structure alteration may be brought about by the action of ATP-dependent multiprotein complexes. One such complex is the mSin3 corepressor complex, which contains mSin3, the histone deacetylases HDAC1 and HDAC2, the associated proteins SAP 30 and SAP 18, and the autoantigens Mi2-α and Mi2-β.

Specifications

Catalog number
ET1704-53
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
ATP dependent helicase CHD4 antibody ATP-dependent helicase CHD4 antibody CHD 4 antibody CHD-4 antibody CHD4 antibody CHD4_HUMAN antibody Chromodomain helicase DNA binding protein 4 antibody Chromodomain-helicase-DNA-binding protein 4 antibody Mi 2 autoantigen 218 kDa protein antibody Mi 2b antibody Mi-2 autoantigen 218 kDa protein antibody Mi2 beta antibody Mi2-beta antibody
Abbreviation
Chromodomain-helicase-DNA-binding protein 4, ATP-dependent helicase CHD4, Mi-2 autoantigen 218 kDa protein, Mi2-beta
Swiss Prot
Q14839 Human, Q6PDQ2 Mouse
Cellular Locus
Nucleus. Cytoplasm.
Host
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Synthetic peptide within human CHD4 aa 1,811-1,860.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IHC-P, FC
Positive Control
293T cell lysate, NIH/3T3 cell lysate, C2C12 cell lysate, 293T, human breast carcinoma tissue, human colon carcinoma tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000 ;IF-Cell: 1:50-1:200 ;IHC-P: 1:50-1:400 ;FC: 1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 218 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for CHD4 Recombinant Rabbit Monoclonal Antibody [JA33-40]?

The catalog number for CHD4 Recombinant Rabbit Monoclonal Antibody [JA33-40] is ET1704-53.

What sizes are available for CHD4 Recombinant Rabbit Monoclonal Antibody [JA33-40]?

CHD4 Recombinant Rabbit Monoclonal Antibody [JA33-40] is available in the following size(s): 100 µL.

Is CHD4 Recombinant Rabbit Monoclonal Antibody [JA33-40] in stock?

CHD4 Recombinant Rabbit Monoclonal Antibody [JA33-40] is currently made to order / not held in immediate stock. Contact us for lead time.

What is CHD4 Recombinant Rabbit Monoclonal Antibody [JA33-40] used for?

In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. A

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

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