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Product details

EAAT1 Recombinant Rabbit Monoclonal Antibody [JA30-35]

Catalog number ET1704-54

Price for ET1704-54

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Size / count 100 µL

About this product

Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na+ ions and one proton, in parallel with the counter-transport of one K+ ion. Mediates Cl- flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na+ symport. Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate. This gene encodes a member of a member of a high affinity glutamate transporter family. This gene functions in the termination of excitatory neurotransmission in central nervous system. Mutations are associated with episodic ataxia, Type 6. Alternative splicing results in multiple transcript variants.

Specifications

Catalog number
ET1704-54
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
GLAST-1 SLC1A3 EAAT1 GLAST GLAST1
Abbreviation
Excitatory amino acid transporter 1, Sodium-dependent glutamate/aspartate transporter 1, Solute carrier family 1 member 3
Swiss Prot
P43003 Human, P56564 Mouse, P24942 Rat
Cellular Locus
Cell membrane.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Human EAAT1 aa 171-220 / 542.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, IF-Tissue, IHC-Fr
Positive Control
Mouse cerebellum tissue, rat cerebellum tissue, human brain tissue, mouse brain tissue, rat brain tissue, Rat cerebellum tissue lysate, Mouse brain tissue lysate, Rat brain tissue lysate.
Concentration
1 mg/mL
Dilution
WB: 1:2,000 ;IHC-P: 1:1,000 ;IF-Tissue: 1:100 ;IHC-Fr: 1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 60 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for EAAT1 Recombinant Rabbit Monoclonal Antibody [JA30-35]?

The catalog number for EAAT1 Recombinant Rabbit Monoclonal Antibody [JA30-35] is ET1704-54.

What sizes are available for EAAT1 Recombinant Rabbit Monoclonal Antibody [JA30-35]?

EAAT1 Recombinant Rabbit Monoclonal Antibody [JA30-35] is available in the following size(s): 100 µL.

Is EAAT1 Recombinant Rabbit Monoclonal Antibody [JA30-35] in stock?

EAAT1 Recombinant Rabbit Monoclonal Antibody [JA30-35] is currently made to order / not held in immediate stock. Contact us for lead time.

What is EAAT1 Recombinant Rabbit Monoclonal Antibody [JA30-35] used for?

Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na+ ions and one proton, in parallel with the counter-transport of one K+ i

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

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