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Product details

Glucose Transporter GLUT3 Recombinant Rabbit Monoclonal Antibody [JA50-31]

Catalog number ET1704-59

Discontinued

Price for ET1704-59

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Size / count 100 µL

This variant is discontinued and cannot be added to your cart.

About this product

Glucose is fundamental to the metabolism of mammalian cells. Its passage across cell membranes is mediated by a family of transporters termed glucose transporters or Gluts. Glut1, Glut3 and Glut4 are high-affinity transporters, whereas Glut2 is a low-affinity transporter. In adipose and muscle tissue, Insulin stimulates a rapid and dramatic increase in glucose uptake, largely due to the redistribution of the Insulin-inducible glucose transporter, Glut4. In response to Insulin, Glut4 is quickly shuttled from an intracellular storage site to the plasma membrane, where it binds glucose. In contrast, the ubiquitously expressed glucose transporter Glut1 is constitutively targeted to the plasma membrane and shows a much less dramatic translocation in response to Insulin. Glut2 expression is seen in pancreatic b cells, hepatocytes and basolateral membranes of intestinal and epithelial cells, while the highest expression of Glut3 has been found in neuronal tissue.

Specifications

Catalog number
ET1704-59
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
Yes
CAS Number
9000-83-3
Product Name Alternative
brain antibody FLJ90380 antibody Glucose transporter type 3 antibody Glucose transporter type 3 brain antibody GLUT 3 antibody GLUT-3 antibody GLUT3 antibody GTR3_HUMAN antibody Slc2a3 antibody Solute Carrier Family 2 (Facilitated Glucose Transporter) Member 3 antibody Solute carrier family 2, facilitated glucose transporter member 3 antibody
Abbreviation
GLUT-3, SLC2A3, GLUT3
Swiss Prot
P11169 Human, P32037 Mouse, Q07647 Rat
Cellular Locus
Cell membrane. Perikaryon. Cell projection.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Human GLUT3 aa 11-60 / 496.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, FC
Positive Control
HepG2 cell lysate, RAW264.7 cell lysate, C6 cell lysate, mouse brain tissue lysate, rat brain tissue lysate, SH-SY5Y.
Concentration
1 mg/mL
Dilution
WB: 1:5,000 ;FC: 1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 54 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Glucose Transporter GLUT3 Recombinant Rabbit Monoclonal Antibody [JA50-31]?

The catalog number for Glucose Transporter GLUT3 Recombinant Rabbit Monoclonal Antibody [JA50-31] is ET1704-59.

Is Glucose Transporter GLUT3 Recombinant Rabbit Monoclonal Antibody [JA50-31] in stock?

Glucose Transporter GLUT3 Recombinant Rabbit Monoclonal Antibody [JA50-31] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Glucose Transporter GLUT3 Recombinant Rabbit Monoclonal Antibody [JA50-31] used for?

Glucose is fundamental to the metabolism of mammalian cells. Its passage across cell membranes is mediated by a family of transporters termed glucose transporters or Gluts. Glut1, Glut3 and Glut4 are high-affinity transporters, whereas Glut2 is a low-affinity transporter. In adipose and muscle tissu

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

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