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![Alpha B Crystallin Recombinant Rabbit Monoclonal Antibody [JA50-32] — image 1 of 3](https://cdn.genprice.uk/products/992/68dd1c8c061270361ea81ad1/imageurl/et1704-60.webp)
Product details
Catalog number ET1704-60
Price for ET1704-60
Size / count 100 µL
Crystallins are the major proteins of the vertebrate eye lens, where they maintain the transparency and refractive index of the lens. Crystallins are divided into α, β and γ families, and the β- and γ-crystallins also compose a superfamily. Crystallins usually contain seven distinct protein regions, inclu-ding four homologous motifs, a connecting peptide, and N- and C-terminal extensions. α-crystallins consist of three gene products, αA-, αB- and αC-crystallin, which are members of the small heat shock protein family (HSP 20). α-crystallins act as molecular chaperones by holding denatured proteins in large soluble aggregates. However, unlike other molecular chaperones, α-crystallins do not renature these proteins. Expression of αA-crystallin is restricted to the lens and defects of this gene cause the development of autosomal dominant congenital cataracts (ADCC). The human αB-crystallin gene product is expressed in many tissues, including lens, heart and skeletal muscle. Elevated expression of αB-crystallin is associated with many neurological diseases, and a missense mutation in this gene has co-segregated in a family with a Desmin-related myopathy.
The catalog number for Alpha B Crystallin Recombinant Rabbit Monoclonal Antibody [JA50-32] is ET1704-60.
Alpha B Crystallin Recombinant Rabbit Monoclonal Antibody [JA50-32] is available in the following size(s): 100 µL.
Alpha B Crystallin Recombinant Rabbit Monoclonal Antibody [JA50-32] is currently made to order / not held in immediate stock. Contact us for lead time.
Crystallins are the major proteins of the vertebrate eye lens, where they maintain the transparency and refractive index of the lens. Crystallins are divided into α, β and γ families, and the β- and γ-crystallins also compose a superfamily. Crystallins usually contain seven distinct protein regions,
Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.
We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.
Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.
