ULK1 Recombinant Rabbit Monoclonal Antibody [JA58-36] — image 1 of 3

Product details

ULK1 Recombinant Rabbit Monoclonal Antibody [JA58-36]

Catalog number ET1704-63

Discontinued

Price for ET1704-63

Size / count 100 µL

This variant is discontinued and cannot be added to your cart.

About this product

Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR. Activated via phosphorylation by AMPK and also acts as a regulator of AMPK by mediating phosphorylation of AMPK subunits PRKAA1, PRKAB2 and PRKAG1, leading to negatively regulate AMPK activity. May phosphorylate ATG13/KIAA0652 and RPTOR; however such data need additional evidences. Plays a role early in neuronal differentiation and is required for granule cell axon formation. May also phosphorylate SESN2 and SQSTM1 to regulate autophagy.

Specifications

Catalog number: ET1704-63
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
CAS Number: 9000-83-3
Product Name Alternative: ATG 1 antibody ATG1 antibody ATG1 autophagy related 1 homolog antibody ATG1A antibody Autophagy related protein 1 homolog antibody Autophagy-related protein 1 homolog antibody FLJ38455 antibody FLJ46475 antibody hATG1 antibody KIAA0722 antibody Serine/threonine protein kinase ULK1 antibody Serine/threonine protein kinase Unc51.1 antibody Serine/threonine-protein kinase ULK1 antibody ULK 1 antibody ULK1 antibody ULK1_HUMAN antibody Unc 51 (C. elegans) like kinase 1 antibody UNC 51 antibody Unc 51 like kinase 1 antibody Unc-51 like kinase 1 (C. elegans) antibody Unc-51-like kinase 1 antibody UNC51 antibody UNC51, C. elegans, homolog of antibody Unc51.1 antibody
Abbreviation: ATG1, hATG1, ULK1, KIAA0722
Swiss Prot: O75385 Human, O70405 Mouse, D3ZMG0 Rat
Cellular Locus: Cytosol, Preautophagosomal structure.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within Human ULK1 aa 930-979 / 1050.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P
Positive Control: A-172 cell lysate, SH-SY5Y cell lysate, U-2 OS cell lysate, MCF7 cell lysate, mouse spleen tissue lysate, rat spleen tissue lysate, human spleen tissue, rat skeletal muscle tissue, human colon carcinoma tissue, mouse brain tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:5,000 ;IHC-P: 1:50-1:200
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 113 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for ULK1 Recombinant Rabbit Monoclonal Antibody [JA58-36]?

The catalog number for ULK1 Recombinant Rabbit Monoclonal Antibody [JA58-36] is ET1704-63.

Is ULK1 Recombinant Rabbit Monoclonal Antibody [JA58-36] in stock?

ULK1 Recombinant Rabbit Monoclonal Antibody [JA58-36] is currently made to order / not held in immediate stock. Contact us for lead time.

What is ULK1 Recombinant Rabbit Monoclonal Antibody [JA58-36] used for?

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.