Bag3 Recombinant Rabbit Monoclonal Antibody [JA90-53] — image 1 of 2

Product details

Bag3 Recombinant Rabbit Monoclonal Antibody [JA90-53]

Catalog number ET1704-73

Price for ET1704-73

Size / count 100 µL

About this product

The Bag family of proteins are characterized by the presence of a 45 amino acid Bag domain through which they bind with high affinity to the ATPase domain of HSP 70, thereby negatively regulating HSP 70 chaperone activity. Bag-3 (Bcl-2-associated athanogene 3), also known as BIS or CAIR-1, is a 575 amino acid protein that contains one C-terminal Bag domain and two N-terminal WW domains. Like other members of the Bag family, Bag-3 functions to inhibit the chaperone activity of HSP 70, specifically by promoting the release of HSP 70-bound substrates. Additionally, Bag-3 exhibits anti-apoptotic activity via cell cycle control, suggesting a possible role for Bag-3 in tumor progression. The gene encoding Bag-3 maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome.

Specifications

Catalog number: ET1704-73
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: BAG 3 antibody BAG family molecular chaperone regulator 3 antibody BAG-3 antibody Bag3 antibody BAG3_HUMAN antibody Bcl 2 binding protein antibody Bcl-2-associated athanogene 3 antibody Bcl-2-binding protein Bis antibody BCL2 associated athanogene 3 antibody BCL2 binding athanogene 3 antibody BIS antibody CAIR 1 antibody Docking protein CAIR 1 antibody Docking protein CAIR-1 antibody MFM6 antibody
Abbreviation: BAG-3, BAG3, BIS
Swiss Prot: O95817 Human, Q9JLV1 Mouse
Cellular Locus: Cytoplasm, Nucleus.
Host: Rabbit
Species Reactivity: Human, Mouse
Immunogen: Synthetic peptide within Human Bag3 aa 71-120 / 575.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P, IP
Positive Control: Neuro-2a cell lysate, mouse heart tissue lysate, MCF-7 cell lysate, Hela cell lysate, human fetal skeletal muscle tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000-1:2,000 ;IHC-P: 1:50-1:200
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 62 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Bag3 Recombinant Rabbit Monoclonal Antibody [JA90-53]?

The catalog number for Bag3 Recombinant Rabbit Monoclonal Antibody [JA90-53] is ET1704-73.

What sizes are available for Bag3 Recombinant Rabbit Monoclonal Antibody [JA90-53]?

Bag3 Recombinant Rabbit Monoclonal Antibody [JA90-53] is available in the following size(s): 100 µL.

Is Bag3 Recombinant Rabbit Monoclonal Antibody [JA90-53] in stock?

Bag3 Recombinant Rabbit Monoclonal Antibody [JA90-53] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Bag3 Recombinant Rabbit Monoclonal Antibody [JA90-53] used for?

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.