CD39 Recombinant Rabbit Monoclonal Antibody [JA90-36]

About this product

CD39, also known as ectonucleoside triphosphate diphosphohydrolase 1 (ENP1), is an integral membrane glycoprotein that acts as an extracellular nucleotide-hydrolyzing enzyme. CD39 inhibits ADP-induced platelet aggregation by hydrolyzing ADP to AMP and ultimately generating adenosine. Intracellular CD39 undergoes glycosylation at 6 N-glycosylation sites and translocates to the membrane in order to be an active enzyme. Alternative splicing gives rise to three CD39 isoforms, vascular, placenta I and placenta II. The placenta I isoform differs at the amino terminus whereas the placenta II isoform is missing amino acids 300-510 at the C-terminus. CD39 is expressed in vascular tissues including placenta, lung, skeletal muscle and kidney, as well as endothelium, smooth muscle, cardiac cells, lymphocytes (such as activated B cells) activated NK cells, macrophages, dendridic cells and platelets. CD39 may be used as an anti-thrombic agent for pre-treating patients at risk for coronary artery occlusion and thrombic stroke.

Specifications

Catalog number

ET1704-74

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

ATPDase antibody CD 39 antibody CD39 antibody CD39 antigen antibody DKFZp686D194 antibody DKFZp686I093 antibody Ecto apyrase antibody Ecto ATP diphosphohydrolase antibody Ecto-apyrase antibody Ecto-ATP diphosphohydrolase 1 antibody Ecto-ATPase 1 antibody Ecto-ATPDase 1 antibody Ectonucleoside triphosphate diphosphohydrolase 1 antibody ENTP1_HUMAN antibody ENTPD 1 antibody ENTPD1 antibody FLJ40921 antibody FLJ40959 antibody Lymphoid cell activation antigen antibody NTPDase 1 antibody NTPDase1 antibody SPG64 antibody

Abbreviation

NTPDase 1, Ecto-ATPDase 1, Ecto-ATPase 1, CD39, ENTPD1

Swiss Prot

P49961 Human, P55772 Mouse, P97687 Rat

Cellular Locus

Membrane.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within Human CD39 aa 371-420 / 510.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P

Positive Control

Mouse lung tissue lysate, mouse placenta tissue lysate, human tonsil tissue, human spleen tissue, human placenta tissue, mouse uterus tissue, human endometrium tissue.

Concentration

1 mg/mL

Dilution

WB: 1:5,000 ;IHC-P: 1:50-1:400

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 58 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes