RBP4 Recombinant Rabbit Monoclonal Antibody [JA33-10]

About this product

Retinol (Vitamin A) is transported in the blood bound to its carrier protein, retinol-binding protein (RBP), also designated plasma retinol-binding protein (PRBP) or RBP4. A member of the lipocalin family, RBP conveys retinol from stores in the liver to peripheral tissues. In plasma, RBP binds transthyretin (TTR, formerly called prealbumin) to prevent glomerular filtration of low molecular weight RBP in the kidneys. The stability of this complex holds diagnostic importance because the molar ratio of RBP:TTR provides an indirect way to indicate marginal vitamin A deficiency. Vitamin A deficiency blocks the secretion of RBP resulting in defective delivery and supply to epidermal cells. Originally identified solely as a transporter protein, recent studies correlating increased levels of RBP expression in adipose tissue with insulin resistance have generated research into the possible roles the protein

Specifications

Catalog number

ET1704-86

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

OTTHUMP00000020114 antibody OTTHUMP00000020115 antibody OTTHUMP00000020116 antibody Plasma retinol binding protein 4 antibody Plasma retinol-binding protein antibody Plasma retinol-binding protein (1-176) antibody PRBP antibody PRO2222 antibody RBP antibody RBP4 antibody RDCCAS antibody RET4_HUMAN antibody Retinol binding protein 4 antibody Retinol binding protein 4 interstitial antibody Retinol binding protein 4 plasma antibody

Abbreviation

PRBP, RBP, RBP4

Swiss Prot

P02753 Human

Cellular Locus

Secreted.

Host

Rabbit

Species Reactivity

Human

Immunogen

Synthetic peptide within Human RBP4 aa152-201 / 201.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P

Positive Control

Human liver carcinoma tissue, human kidney tissue, human liver tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:2,000 ;IHC-P: 1:50-1:200

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

23 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes