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Product details

5HT2C Receptor Recombinant Rabbit Monoclonal Antibody [JA31-31]

Catalog number ET1704-87

Price for ET1704-87

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Size / count 100 µL

About this product

G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including ergot alkaloid derivatives, 1-2,5,-dimethoxy-4-iodophenyl-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and down-stream signaling cascades and promotes the release of Ca2+ ions from intracellular stores. Regulates neuronal activity via the activation of short transient receptor potential calcium channels in the brain, and thereby modulates the activation of pro-opiomelacortin neurons and the release of CRH that then regulates the release of corticosterone.

Specifications

Catalog number
ET1704-87
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
5 Hydroxytryptamine 2C receptor antibody 5-HT-1C antibody 5-ht-1c receptor antibody 5-HT-2C antibody 5-HT1C antibody 5-HT2C antibody 5-HTR2C antibody 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled antibody 5-hydroxytryptamine receptor 1C antibody 5-hydroxytryptamine receptor 2C antibody 5HT1C antibody 5HT2C antibody 5HT2C_HUMAN antibody 5HTR2C antibody 5Hydroxytryptamine 2C receptor antibody Htr1c antibody HTR2C antibody serotonin 1c receptor antibody serotonin 2c receptor antibody Serotonin 5-HT-2C receptor antibody Serotonin receptor 2C antibody
Abbreviation
5-HT-2C, 5-HT2C, 5-HTR2C, 5-HT-1C, 5-HT1C, HTR2C, HTR1C
Swiss Prot
P28335 Human, P34968 Mouse, P08909 Rat
Cellular Locus
Cell membrane.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Human 5HT2C Receptor aa 409-458 / 458.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P
Positive Control
K-562 cell lysate, SH-SY5Y cell lysate, human brain tissue lysate, mouse brain tissue, rat brain tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000 ;IHC-P: 1:50
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 52 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for 5HT2C Receptor Recombinant Rabbit Monoclonal Antibody [JA31-31]?

The catalog number for 5HT2C Receptor Recombinant Rabbit Monoclonal Antibody [JA31-31] is ET1704-87.

What sizes are available for 5HT2C Receptor Recombinant Rabbit Monoclonal Antibody [JA31-31]?

5HT2C Receptor Recombinant Rabbit Monoclonal Antibody [JA31-31] is available in the following size(s): 100 µL.

Is 5HT2C Receptor Recombinant Rabbit Monoclonal Antibody [JA31-31] in stock?

5HT2C Receptor Recombinant Rabbit Monoclonal Antibody [JA31-31] is currently made to order / not held in immediate stock. Contact us for lead time.

What is 5HT2C Receptor Recombinant Rabbit Monoclonal Antibody [JA31-31] used for?

G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including ergot alkaloid derivatives, 1-2,5,-dimethoxy-4-iodophenyl-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformat

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

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