Peroxiredoxin 3 Recombinant Rabbit Monoclonal Antibody [JA53-21]

About this product

Thioredoxin-dependent peroxide reductase, mitochondrial is an enzyme that in humans is encoded by the PRDX3 gene. It is a member of the peroxiredoxin family of antioxidant enzymes. This gene encodes a protein with antioxidant function and is localized in the mitochondrion. This gene shows significant nucleotide sequence similarity to the gene coding for the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase. Expression of this gene product in E. coli deficient in the C22-subunit gene rescued resistance of the bacteria to alkylhydroperoxide. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologues suggest that these genes consist of a family that is responsible for regulation of cellular proliferation, differentiation, and antioxidant functions. Two transcript variants encoding two different isoforms have been found for this gene.

Specifications

Catalog number

ET1704-92

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

Antioxidant protein 1 antibody AOP 1 antibody AOP-1 antibody AOP1 antibody HBC189 antibody MER5 antibody MGC104387 antibody MGC24293 antibody mitochondrial antibody peroxiredoxin 3 antibody Peroxiredoxin III antibody Peroxiredoxin-3 antibody PRDX3 antibody PRDX3_HUMAN antibody PRO1748 antibody Protein MER5 homolog antibody PRX III antibody Prx-III antibody PRX3 antibody SP 22 antibody SP-22 antibody SP22 antibody Thioredoxin dependent peroxide reductase mitochondrial antibody Thioredoxin-dependent peroxide reductase antibody

Abbreviation

AOP-1, Prx-III, PRDX3, AOP1

Swiss Prot

P30048 Human

Cellular Locus

Mitochondrion.

Host

Rabbit

Species Reactivity

Human

Immunogen

Synthetic peptide within Human Peroxiredoxin 3 aa 207-256 / 256.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IHC-P, FC, IP

Positive Control

MCF-7 cell lysate, A431 cell lysate, Hela, HepG2, MCF-7, human liver tissue, human liver carcinoma tissue, human kidney tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:2,000;IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200;FC: 1:50-1:100;IP: Use at an assay dependent concentration.

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 28 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes