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Product details

DOPA Decarboxylase Recombinant Rabbit Monoclonal Antibody [JA53-16]

Catalog number ET1704-94

Price for ET1704-94

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Size / count 100 µL

About this product

DOPA decarboxylase (DDC), also designated aromatic-L-amino-acid decarboxylase (AADC) belongs to the group II decarboxylase family of proteins. DDC, which can form a homodimer, is an important protein in the catecholamine biosynthesis pathway. DDC acts as a catalyst in the decarboxylation of L-5-hydroxytryptophan to serotonin, L-3,4-dihydroxyphenylalanine (DOPA) to dopamine and L-tryptophan to tryptamine. Defects in the gene encoding for DDC may cause the autosomal recessive disorder AADC deficiency. AADC deficiency is an early onset inborn error in neurotransmitter metabolism which can lead to catecholamine and serotonin deficiency. This causes poor feeding, psychomotor and developmental delays, lethargy, ptosis, gastrointestinal disturbances and hypothermia.

Specifications

Catalog number
ET1704-94
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
AADC antibody Aromatic L Amino Acid Decarboxylase antibody Aromatic-L-amino-acid decarboxylase antibody Ddc antibody DDC_HUMAN antibody DOPA decarboxylase (aromatic L-amino acid decarboxylase) antibody DOPA decarboxylase antibody
Abbreviation
AADC, DDC
Swiss Prot
P20711 Human, O88533 Mouse, P14173 Rat
Cellular Locus
Cytoplasm.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Human DOPA Decarboxylase aa 27-76 / 480.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P
Positive Control
Human kidney tissue, human liver tissue, mouse liver tissue lysates, HepG2 cell lysates.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000 ;IHC-P: 1:50-1:400
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 54 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for DOPA Decarboxylase Recombinant Rabbit Monoclonal Antibody [JA53-16]?

The catalog number for DOPA Decarboxylase Recombinant Rabbit Monoclonal Antibody [JA53-16] is ET1704-94.

What sizes are available for DOPA Decarboxylase Recombinant Rabbit Monoclonal Antibody [JA53-16]?

DOPA Decarboxylase Recombinant Rabbit Monoclonal Antibody [JA53-16] is available in the following size(s): 100 µL.

Is DOPA Decarboxylase Recombinant Rabbit Monoclonal Antibody [JA53-16] in stock?

DOPA Decarboxylase Recombinant Rabbit Monoclonal Antibody [JA53-16] is currently made to order / not held in immediate stock. Contact us for lead time.

What is DOPA Decarboxylase Recombinant Rabbit Monoclonal Antibody [JA53-16] used for?

DOPA decarboxylase (DDC), also designated aromatic-L-amino-acid decarboxylase (AADC) belongs to the group II decarboxylase family of proteins. DDC, which can form a homodimer, is an important protein in the catecholamine biosynthesis pathway. DDC acts as a catalyst in the decarboxylation of L-5-hydr

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

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