PKC beta 1 Recombinant Rabbit Monoclonal Antibody [JM43-26]

About this product

Protein kinase C beta type is an enzyme that in humans is encoded by the PRKCB gene. Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported. This gene could be associated with autism.

Specifications

Catalog number

ET1705-30

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

BTN6 antibody BTNL11 antibody MGC26137 antibody MOG alpha 5 antibody MOG alpha 6 antibody MOG AluA antibody MOG AluB antibody MOG antibody MOG Ig AluB antibody MOG_HUMAN antibody MOGIG2 antibody Myelin oligodendrocyte glycoprotein antibody Myelin-oligodendrocyte glycoprotein antibody NRCLP7 antibody

Abbreviation

PKC-B, PKC-beta, PRKCB, PKCB, PRKCB1

Swiss Prot

P05771 Human, P68404 Mouse, P68403 Rat

Cellular Locus

Cytoplasm. Nucleus. Membrane.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within Human PKC beta 1 aa 608-657 / 671.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P, FC

Positive Control

L929 cell lysates, human tonsil tissue, human spleen tissue, mouse kidney tissue, K562.

Concentration

1 mg/mL

Dilution

WB: 1:500 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 77 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes