Ephrin B2 Recombinant Rabbit Monoclonal Antibody [JM53-21]

About this product

Ephrin-B2 is a protein that in humans is encoded by the EFNB2 gene. This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNB class ephrin which binds to the EPHB4 and EPHA3 receptors. EFNB2 gene has been observed progressively downregulated in Human papillomavirus-positive neoplastic keratinocytes derived from uterine cervical preneoplastic lesions at different levels of malignancy. For this reason, EFNB2 is likely to be associated with tumorigenesis and may be a potential prognostic marker for uterine cervical preneoplastic lesions progression.

Specifications

Catalog number

ET1705-33

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

Yes

CAS Number

9000-83-3

Product Name Alternative

EFN B2 antibody EFNB 2 antibody Efnb2 antibody EFNB2_HUMAN antibody Eph related receptor tyrosine kinase ligand 5 antibody EPH-related receptor tyrosine kinase ligand 5 antibody ephrin B2 antibody Ephrin-B2 antibody EphrinB2 antibody EPLG 5 antibody EPLG5 antibody Htk L antibody HTK ligand antibody HTK-L antibody HTKL antibody LERK 5 antibody LERK-5 antibody LERK5 antibody Ligand of eph related kinase 5 antibody MGC126226 antibody MGC126227 antibody MGC126228 antibody OTTMUSP00000024973 antibody

Abbreviation

LERK-5, HTK-L, EFNB2, EPLG5, HTKL, LERK5

Swiss Prot

P52799 Human, P52800 Mouse, B2B9A9 Rat

Cellular Locus

Membrane.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within Human Ephrin B aa 47-96 / 333.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell

Positive Control

SH-SY5Y cell lysate, SK-OV-3 cell lysate, mouse lung tissue lysate, rat brain tissue lysate, HeLa, Neuro-2a, C6.

Concentration

1 mg/mL

Dilution

WB: 1:2,000 ;IF-Cell: 1:50-1:200

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 37 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes