USP11 Recombinant Rabbit Monoclonal Antibody [JM33-62]

About this product

Ubiquitin carboxyl-terminal hydrolase or Ubiquitin specific protease 11 is an enzyme that in humans is encoded by the USP11 gene. USP11 belongs to the Ubiquitin specific proteases family (USPs) which is a sub-family of the Deubiquitinating enzymes (DUBs).USPs are multiple domain proteases and belong to the C19 cysteine proteases sub‒family. Depending on their domain architecture and position there is different homology between the various members. Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates. This gene encodes a deubiquitinating enzyme which lies in a gene cluster on chromosome Xp11.23.

Specifications

Catalog number

ET1705-38

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

Deubiquitinating enzyme 11 antibody Ubiquitin carboxyl-terminal hydrolase 11 antibody Ubiquitin carboxyl-terminal hydrolase X linked antibody ubiquitin specific peptidase 11 antibody Ubiquitin specific protease 11 antibody Ubiquitin thiolesterase 11 antibody Ubiquitin-specific-processing protease 11 antibody UBP11_HUMAN antibody UHX1 antibody USP11 antibody

Abbreviation

USP11, UHX1

Swiss Prot

P51784 Human, Q99K46 Mouse

Cellular Locus

Nucleus. Cytoplasm. Predominantly nuclear.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within Human USP11 aa 879-928 / 963.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IHC-P, FC, IP

Positive Control

293T cell lysates, A549, HepG2, SH-SY5Y, mouse brain tissue, rat testis tissue, Jurkat.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:1,000;IF-Cell: 1:50-1:200;IF-Tissue: 1:50-1:200;IHC-P: 1:100-1:500;FC: 1:50-1:100;IP: Use at an assay dependent concentration.

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 110 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes