SKP1 Recombinant Rabbit Monoclonal Antibody [JM27-37]

About this product

S-phase kinase-associated protein 1 is an enzyme that in humans is encoded by the SKP1 gene. This gene encodes a protein that is a member of the SCF ubiquitin ligase protein complex. It binds to F-box proteins (proteins containing an F-box motif), such as cyclin F, S-phase kinase-associated protein 2, and other regulatory proteins involved in ubiquitin dependent proteolysis. The encoded protein also collaborates with a network of proteins to control beta-catenin levels and affects the activity level of beta-catenin dependent TCF transcription factors. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7.

Specifications

Catalog number

ET1705-43

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

Cyclin A/CDK2 associated p19 antibody Cyclin A/CDK2 associated protein p19 antibody Cyclin-A/CDK2-associated protein p19 antibody EMC19 antibody MGC34403 antibody OCP 2 antibody OCP II antibody OCP II protein antibody OCP-2 antibody OCP-II antibody OCP2 antibody OCPII antibody Organ of Corti protein 2 antibody Organ of Corti protein II antibody OTTHUMP00000159379 antibody OTTHUMP00000159380 antibody OTTHUMP00000228275 antibody OTTHUMP00000228276 antibody OTTHUMP00000228278 antibody OTTHUMP00000228279 antibody OTTHUMP00000228281 antibody p19A antibody p19skp1 antibody RNA polymerase II elongation factor like protein antibody RNA polymerase II elongation factor like protein OCP2 antibody RNA polymerase II elongation factor-like protein antibody S phase kinase associated protein 1 antibody S phase kinase associated protein 1A antibody S phase kinase associated protein 1A p19A antibody S-phase kinase-associated protein 1 antibody SIII antibody Skp 1 antibody SKP 1A antibody skp1 antibody SKP1_HUMAN antibody SKP1A antibody TCEB1L antibody Transcription Elongation Factor B 1 like antibody Transcription elongation factor B antibody Transcription elongation factor B SIII polypeptide 1 like antibody

Abbreviation

p19A, OCP-2, OCP-II, SKP1, EMC19, OCP2, SKP1A, TCEB1L

Swiss Prot

P63208 Human, Q9WTX5 Mouse, Q6PEC4 Rat

Cellular Locus

Cytoplasm. Nucleus.

Host

Rabbit

Species Reactivity

Human, Rat, Mouse

Immunogen

Synthetic peptide within Human Skp1 aa 106-155 / 163.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IHC-P, FC

Positive Control

PC-12 cell lysates, Hela, SH-SY5Y, human breast tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500 ;IF-Cell: 1:50-1:100 ;IF-Tissue: 1:50-1:100 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 19 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes