NFkB p100 Recombinant Rabbit Monoclonal Antibody [JM82-03]

About this product

Nuclear factor NF-kappa-B p100 subunit is a protein that in humans is encoded by the NFKB2 gene. NF-κB has been detected in numerous cell types that express cytokines, chemokines, growth factors, cell adhesion molecules, and some acute phase proteins in health and in various disease states. NF-κB is activated by a wide variety of stimuli such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NF-kappa-B has been linked to inflammatory events associated with autoimmune arthritis, asthma, septic shock, lung fibrosis, glomerulonephritis, atherosclerosis, and AIDS. In contrast, complete and persistent inhibition of NF-kappa-B has been linked directly to apoptosis, inappropriate immune cell development, and delayed cell growth.

Specifications

Catalog number

ET1705-45

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

CVID10 antibody DNA binding factor KBF2 antibody H2TF1 antibody Lymphocyte translocation chromosome 10 protein antibody LYT 10 antibody NF kB2 antibody NFKB p52/p100 subunit antibody Nuclear factor Kappa B subunit 2 antibody Nuclear factor of kappa light polypeptide gene enhancer in B cells 2 (p49/p100) antibody Nuclear factor of kappa light polypeptide gene enhancer in B cells 2 antibody Oncogene Lyt 10 antibody p100 antibody Transcription factor NFKB2 antibody

Abbreviation

Lyt10, NFKB2, LYT10

Swiss Prot

Q00653 Human, Q9WTK5 Mouse,

Cellular Locus

Cytoplasm. Nucleus.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein within Human NFkB p100 aa 725-897 / 900.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IHC-P, IP

Positive Control

MCF7 cell lysate, THP-1 cell lysate, Mouse kidney tissue lysate, Rat heart tissue lysate, Rat spleen tissue lysate, A431, human colon cancer tissue, mouse thymus tissue, human tonsil tissue, human placenta tissue.

Concentration

1 mg/mL

Dilution

WB: 1:1,000 ;IF-Cell: 1:50-1:200 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:50-1:200 ;IP: Use at an assay dependent concentration.

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 97 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes