KMT5A/SETD8/Pr-SET7 Recombinant Rabbit Monoclonal Antibody [JM73-43] — image 1 of 2

Product details

KMT5A/SETD8/Pr-SET7 Recombinant Rabbit Monoclonal Antibody [JM73-43]

Catalog number ET1705-59

Price for ET1705-59

Size / count 100 µL

About this product

Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. All monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions , benef playing a central role in the silencing of euchromatic genes. Required for cell proliferation, probably by contribute to the maintenance of proper higher order structure of DNA during mitosis. Involved in chromosome condensation and proper cytokinesis. Nucleosomes are preferred as substrate compared to free histones. Mediates monomethylation of p53 / TP53 at 'Lys-382', leading to repress p53 / TP53-target genes.

Specifications

Catalog number: ET1705-59
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: H4 K20 HMTase antibody H4 K20 specific histone methyltransferase antibody H4-K20-HMTase SETD8 antibody Histone H4 K20 methyltransferase antibody Histone lysine N methyltransferase H4 lysine 20 specific antibody Histone-lysine N-methyltransferase SETD8 antibody Lysine N-methyltransferase 5A antibody N-lysine methyltransferase SETD8 antibody Pr SET 7 antibody Pr SET7 antibody PR-Set7 antibody PR/SET domain containing protein 07 antibody PR/SET domain containing protein 8 antibody PR/SET domain-containing protein 07 antibody PR/SET07 antibody PrSET7 antibody SET 07 antibody SET 8 antibody SET domain containing (lysine methyltransferase) 8 antibody SET domain containing 8 antibody SET domain containing lysine methyltransferase 8 antibody SET domain containing protein 8 antibody SET domain-containing protein 8 antibody SET07 antibody SET8 antibody SETD 8 antibody setd8 antibody SETD8_HUMAN antibody
Abbreviation: PR-Set7, PR/SET07, KMT5A, PRSET7, SET07, SET8, SETD8
Swiss Prot: Q9NQR1 Human, Q2YDW7 Mouse
Cellular Locus: Nucleus.
Host: Rabbit
Species Reactivity: Human, Mouse
Immunogen: Synthetic peptide within Human KMT5A aa 51-100 / 393.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, FC
Positive Control: Mouse kidney tissue lysates, Mouse liver tissue lysates, 293T cell lysates, 293 cell lysates, 293T cells.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:2,000 ;FC: 1:50-1:100
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 43 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for KMT5A/SETD8/Pr-SET7 Recombinant Rabbit Monoclonal Antibody [JM73-43]?

The catalog number for KMT5A/SETD8/Pr-SET7 Recombinant Rabbit Monoclonal Antibody [JM73-43] is ET1705-59.

What sizes are available for KMT5A/SETD8/Pr-SET7 Recombinant Rabbit Monoclonal Antibody [JM73-43]?

KMT5A/SETD8/Pr-SET7 Recombinant Rabbit Monoclonal Antibody [JM73-43] is available in the following size(s): 100 µL.

Is KMT5A/SETD8/Pr-SET7 Recombinant Rabbit Monoclonal Antibody [JM73-43] in stock?

KMT5A/SETD8/Pr-SET7 Recombinant Rabbit Monoclonal Antibody [JM73-43] is currently made to order / not held in immediate stock. Contact us for lead time.

What is KMT5A/SETD8/Pr-SET7 Recombinant Rabbit Monoclonal Antibody [JM73-43] used for?

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.