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![PFKFB3 Recombinant Rabbit Monoclonal Antibody [JM43-43] — image 1 of 3](https://cdn.genprice.uk/products/992/68dd1c8a061270361ea80f1a/imageurl/et1705-66.webp)
Product details
Catalog number ET1705-66
Price for ET1705-66
Size / count 100 µL
Among the enzymes playing role in glycolysis,four allosteric PFKFB enzymes 1–4 expressed by four independent PFKFB genes, catalyze the rate-limiting phosphorylation of fructose-6-phosphate to fructose-1, 6-bisphosphate, using ATP as the energy source in the glycolysis pathway. Among these four allosteric enzymes, PFKFB3 enzyme retains the highest Kinase/Biphosphatase activity ratio and is expressed by PFKFB3 gene which has been demonstrated to be highly expressed in leukemic cells and in solid tumors. Moreover, mitogenic, hypoxic and inflammatory conditions have an inductive effect on the expression of PFKFB3. Hence upregulation of PFKFB genes specific to cancer cells compared to their normal counterparts (from the same patients) with more robust over-expression in breast and lung cancer make it a more appropriate target.
The catalog number for PFKFB3 Recombinant Rabbit Monoclonal Antibody [JM43-43] is ET1705-66.
PFKFB3 Recombinant Rabbit Monoclonal Antibody [JM43-43] is available in the following size(s): 100 µL.
PFKFB3 Recombinant Rabbit Monoclonal Antibody [JM43-43] is currently made to order / not held in immediate stock. Contact us for lead time.
Among the enzymes playing role in glycolysis,four allosteric PFKFB enzymes 1–4 expressed by four independent PFKFB genes, catalyze the rate-limiting phosphorylation of fructose-6-phosphate to fructose-1, 6-bisphosphate, using ATP as the energy source in the glycolysis pathway. Among these four allos
If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.
The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.
A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.
