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Product details

MVP Recombinant Rabbit Monoclonal Antibody [JM74-73]

Catalog number ET1705-69

Price for ET1705-69

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Size / count 100 µL

About this product

Major vault protein (MVP), is overexpressed in various multidrug-resistant cancer cell lines and clinical samples. The promoter of MVP is TATA-less; contains an inverted CCAAT-box and a Sp1 site located near a p53 binding motif. MVP has two alternative splice variants, which differ from each other within the 5'-leader. The long-MVP isoform is ubiquitously expressed and represents an almost constant portion of the total MVP mRNA in many different normal tissues. MVP is the major component of the multimeric ribonucleoprotein complexes, with several copies of an untranslated RNA, which has been shown to transport along cytoskeletal-based cellular tracks. In conclusion, MVP protein mediates drug resistance, perhaps via a transport process.

Specifications

Catalog number
ET1705-69
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
LRP antibody Lung resistance related protein antibody Lung resistance-related protein antibody Major vault protein antibody Major vault protein, rat, homolog of antibody MVP antibody MVP_HUMAN antibody testicular secretory protein Li 30 antibody VAULT 1 antibody VAULT1 antibody
Abbreviation
MVP, LRP
Swiss Prot
Q14764 Human, Q9EQK5 Mouse, Q62667 Rat
Cellular Locus
Cytoplasm, Nuclear pore complex, Nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Human MVP aa 13-62 / 893.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P
Positive Control
A549 cell lysate, PC-12 cell lysate, Hela cell lysate, mouse lung tissue lysate, human colon carcinoma tissue, human stomach carcinoma tissue, mouse colon tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000 ;IHC-P: 1:50-1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 99 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for MVP Recombinant Rabbit Monoclonal Antibody [JM74-73]?

The catalog number for MVP Recombinant Rabbit Monoclonal Antibody [JM74-73] is ET1705-69.

What sizes are available for MVP Recombinant Rabbit Monoclonal Antibody [JM74-73]?

MVP Recombinant Rabbit Monoclonal Antibody [JM74-73] is available in the following size(s): 100 µL.

Is MVP Recombinant Rabbit Monoclonal Antibody [JM74-73] in stock?

MVP Recombinant Rabbit Monoclonal Antibody [JM74-73] is currently made to order / not held in immediate stock. Contact us for lead time.

What is MVP Recombinant Rabbit Monoclonal Antibody [JM74-73] used for?

Major vault protein (MVP), is overexpressed in various multidrug-resistant cancer cell lines and clinical samples. The promoter of MVP is TATA-less; contains an inverted CCAAT-box and a Sp1 site located near a p53 binding motif. MVP has two alternative splice variants, which differ from each other w

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

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