RANTES Recombinant Rabbit Monoclonal Antibody [JM03-45]

About this product

Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. Binds to CCR1, CCR3, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form RANTES (3-68) acts as a natural chemotaxis inhibitor and is a more potent inhibitor of HIV-1-infection. The second processed form RANTES (4-68) exhibits reduced chemotactic and HIV-suppressive activity compared with RANTES (1-68) and RANTES (3-68) and is generated by an unidentified enzyme associated with monocytes and neutrophils.

Specifications

Catalog number

ET1705-70

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

Beta chemokine RANTES antibody Beta chemokine RANTES precursor antibody C C motif chemokine 5 antibody CCL 5 antibody CCL5 antibody CCL5_HUMAN antibody Chemokine (C C motif) ligand 5 antibody Chemokine CC Motif Ligand 5 antibody D17S136E antibody EoCP antibody Eosinophil chemotactic cytokine antibody MGC17164 antibody RANTES (4-68) antibody Regulated upon activation normally T expressed and presumably secreted antibody SCYA 5 antibody SCYA5 antibody SIS delta antibody SIS-delta antibody SISd antibody Small inducible cytokine A5 (RANTES) antibody Small inducible cytokine A5 antibody Small inducible cytokine subfamily A (Cys Cys) member 5 antibody Small-inducible cytokine A5 antibody T cell specific protein p288 antibody T cell specific RANTES protein antibody T cell-specific protein P228 antibody T-cell-specific protein RANTES antibody TCP 228 antibody TCP228 antibody

Abbreviation

TCP228, CCL5, D17S136E, SCYA5

Swiss Prot

P13501 Human, P30882 Mouse

Cellular Locus

Secreted.

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant protein within human RANTES aa 1-91.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P, IF-Cell, IF-Tissue

Positive Control

Mouse thymus lysates, Hela, HUVEC, human tonsil tissue, human placenta tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:1,000 ;IF-Cell: 1:50-1:200 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:50-1:200

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 10 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes