ALIX Recombinant Rabbit Monoclonal Antibody [JM85-31]

About this product

ALG-2-interacting protein (Alix), also designated programmed cell death 6-interacting protein (PDCD6-interacting protein), is a cytoplasmic protein. Alix interacts with apoptosis-associated proteins (ALG-2 and PDCD6) and with the endocytosis-regulator CIN85. Additionally, Alix interacts with the endosomal sorting complexes required for transport (ESCRT) proteins (Tsg101 and CHMP4) and can associate with HIV-1. The endophilins (SH3P4, SH3P8 and SH3P13), enzymes that change curvature of the membrane that are required for early and late steps of coated vesicle formation, also bind to Alix. Alix is involved in the concentration and sorting of cargo proteins of the multivesicular body for incorporation into vesicles.

Specifications

Catalog number

ET1705-74

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

Yes

CAS Number

9000-83-3

Product Name Alternative

AIP1 antibody ALG 2 interacting protein 1 antibody ALG-2-interacting protein 1 antibody ALG2 interacting protein X antibody Alix antibody Apoptosis linked gene 2 interacting protein X antibody Dopamine receptor interacting protein 4 antibody DRIP4 antibody Hp95 antibody KIAA1375 antibody MGC17003 antibody PDC6I_HUMAN antibody PDCD6 interacting protein antibody PDCD6-interacting protein antibody PDCD6IP antibody Programmed cell death 6 interacting protein antibody Programmed cell death 6-interacting protein antibody

Abbreviation

PDCD6-interacting protein, PDCD6IP, AIP1, ALIX, KIAA1375

Swiss Prot

Q8WUM4 Human, Q9WU78 Mouse, Q9QZA2 Rat

Cellular Locus

Cell junction, Cytoplasm, Cytoskeleton, Secreted, Tight junction.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein within Human ALIX aa 1-160 / 868.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P, FC, IF-Cell

Positive Control

HEK-293 cell lysate, K-562 cell lysate, Jurkat cell lysate, PC-3M cell lysate, MCF7 cell lysate, NIH/3T3 cell lysate, PC-12 cell lysate, mouse liver tissue lysate, rat liver tissue lysate, rat stomach tissue, human colon carcinoma tissue, human prostate tissue, MCF7, NIH/3T3, PC-12, HEK-293..

Concentration

1 mg/mL

Dilution

WB: 1:1,000-1:2,000 ;IHC-P: 1:50-1:200 ;FC: 1:1,000 ;IF-Cell: 1:100

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 96 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes