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Product details

Epac1 Recombinant Rabbit Monoclonal Antibody [JM63-29]

Catalog number ET1705-79

Price for ET1705-79

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Size / count 100 µL

About this product

3',5' cyclic adenosine monophosphate (cAMP)-regulated guanine nucleotide exchange factors Epac (Epac1, cAMP-GEFI) and Epac2 (cAMP-GEFII) activate the Ras family GTPases Rap 1 and Rap 2 by promoting GTP binding in a cAMP-dependent manner. Eukaryotic cAMP is a second messenger that induces physiological responses such as gene expression, growth, differentiation, secretion and neurotransmission. The human Epac gene maps to chromosome 12q13.11 with transcript being abundant in the kidney and heart. In situ hybridization indicates expression of Epac in adult rat brain and selective expression in neonatal brain, including septum and thalamus.

Specifications

Catalog number
ET1705-79
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
bcm910 antibody CAMP GEFI antibody cAMP regulated guanine nucleotide exchange factor I antibody CAMPGEFI antibody CGEF 1 antibody CGEF1 antibody EPA1 antibody Epac 1 antibody EPAC antibody EPAC1 antibody Exchange factor directly activated by cAMP 1 antibody Exchange protein directly activated by cAMP 1 antibody MGC21410 antibody RAP guanine nucleotide exchange factor antibody Rap guanine nucleotide exchange factor (GEF) 3 antibody RAP guanine nucleotide exchange factor 3 antibody Rap1 guanine nucleotide exchange factor directly activated by cAMP antibody RAPGEF3 antibody
Abbreviation
EPAC 1, cAMP-GEFI, RAPGEF3, CGEF1, EPAC, EPAC1
Swiss Prot
O95398 Human, Q8VCC8 Mouse, Q9Z1C8 Rat
Cellular Locus
Endomembrane system.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Human Epac1 aa 874-923 / 923.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, IF-Tissue
Positive Control
HUVEC cell lysate, mouse kidney tissue lysate, rat brain tissue lysate, human prostate tissue, human stomach carcinoma tissue, mouse kidney tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IHC-P: 1:50-1:200 ;IF-Tissue: 1:10-1:50
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 104 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Epac1 Recombinant Rabbit Monoclonal Antibody [JM63-29]?

The catalog number for Epac1 Recombinant Rabbit Monoclonal Antibody [JM63-29] is ET1705-79.

What sizes are available for Epac1 Recombinant Rabbit Monoclonal Antibody [JM63-29]?

Epac1 Recombinant Rabbit Monoclonal Antibody [JM63-29] is available in the following size(s): 100 µL.

Is Epac1 Recombinant Rabbit Monoclonal Antibody [JM63-29] in stock?

Epac1 Recombinant Rabbit Monoclonal Antibody [JM63-29] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Epac1 Recombinant Rabbit Monoclonal Antibody [JM63-29] used for?

3',5' cyclic adenosine monophosphate (cAMP)-regulated guanine nucleotide exchange factors Epac (Epac1, cAMP-GEFI) and Epac2 (cAMP-GEFII) activate the Ras family GTPases Rap 1 and Rap 2 by promoting GTP binding in a cAMP-dependent manner. Eukaryotic cAMP is a second messenger that induces physiologic

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

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