GCLM Recombinant Rabbit Monoclonal Antibody [JM39-61] — image 1 of 3

Product details

GCLM Recombinant Rabbit Monoclonal Antibody [JM39-61]

Catalog number ET1705-87

Price for ET1705-87

Size / count 100 µL

About this product

Gamma-glutamylcysteine synthetase (γ-GCS) is the rate limiting enzyme for glutathione (L-gamma-glutamyl-L-cysteinylglycine, GSH) synthesis. GSH is ubiquitous in mammalian cells as a vital intra- and extracellular protective antioxidant. γ-GCS is a heterodimer of a heavy catalytic subunit and a light regulatory subunit that is responsive to inflammation, phenolic antioxidants, heat shock, oxidants and cytokines. The human gamma-GCS gene encoding the 367 amino acid catalytic subunit maps to chromosome 6p12. The human γ-GCS gene encoding the regulatory subunit maps to chromosome 1p22-p21. The two subunits of γ-GCS form a heterodimeric zinc metalloprotein that gains activity through formation of a reversible disulfide bond.

Specifications

Catalog number: ET1705-87
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: Gamma ECS regulatory subunit antibody Gamma-ECS regulatory subunit antibody Gamma-glutamylcysteine synthetase regulatory subunit antibody GCLM antibody GCS light chain antibody GLCLR antibody Glutamate cysteine ligase regulatory subunit antibody Glutamate--cysteine ligase modifier subunit antibody Glutamate--cysteine ligase regulatory subunit antibody GSC light chain antibody GSH0_HUMAN antibody
Abbreviation: GCLM, GLCLR
Swiss Prot: P48507 Human, O09172 Mouse, P48508 Rat
Cellular Locus: Cytosol.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within Human GCLM aa 225-274 / 274.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Tissue, IHC-P, IP, IHC-Fr
Positive Control: A431 cell lysate, NIH/3T3 cell lysate, PC-12 cell lysate, HeLa cell lysate, Mouse liver tissue lysate, Rat liver tissue lysate, human liver tissue, human lung tissue, mouse liver tissue, rat liver tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000-1:2,000 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:200-1:1,000 ;IP: Use at an assay dependent concentration. ;IHC-Fr: 1:50
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 31 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for GCLM Recombinant Rabbit Monoclonal Antibody [JM39-61]?

The catalog number for GCLM Recombinant Rabbit Monoclonal Antibody [JM39-61] is ET1705-87.

What sizes are available for GCLM Recombinant Rabbit Monoclonal Antibody [JM39-61]?

GCLM Recombinant Rabbit Monoclonal Antibody [JM39-61] is available in the following size(s): 100 µL.

Is GCLM Recombinant Rabbit Monoclonal Antibody [JM39-61] in stock?

GCLM Recombinant Rabbit Monoclonal Antibody [JM39-61] is currently made to order / not held in immediate stock. Contact us for lead time.

What is GCLM Recombinant Rabbit Monoclonal Antibody [JM39-61] used for?

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.