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Product details

FTO Recombinant Rabbit Monoclonal Antibody [JM98-30]

Catalog number ET1705-89

Price for ET1705-89

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Size / count 100 µL

About this product

FTO, also known as Fatso or KIAA1752, is a 505 amino acid protein that has an N-terminal nuclear localization signal. Expressed in a variety of tissues, with highest levels present in brain and pancreatic tissue, Fatso exists as four alternatively spliced isoforms, one of which is associated with a predisposition to childhood and adult obesity. Due to its involvement in the development of obesity, Fatso is associated with an increased BMI and may be involved in the pathogenesis of type 2 diabetes. The gene encoding Fatso maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.

Specifications

Catalog number
ET1705-89
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
AlkB homolog 9 antibody ALKBH9 antibody Alpha-ketoglutarate-dependent dioxygenase FTO antibody AW743446 antibody Fat mass and obesity-associated protein antibody FATSO, MOUSE, HOMOLOG OF antibody Fto antibody FTO_HUMAN antibody GDFD antibody KIAA1752 antibody mKIAA1752 antibody Protein fatso antibody
Abbreviation
FTO, KIAA1752
Swiss Prot
Q9C0B1 Human
Cellular Locus
Cytoplasm, Nucleus.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within Human FTO aa 1-50 / 505.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P
Positive Control
HepG2 cell lysate, 293 cell lysate, human brain tissue lysate, human placenta tissue, human pancreas tissue, human uterus tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000 ;IHC-P: 1:50-1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 58 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for FTO Recombinant Rabbit Monoclonal Antibody [JM98-30]?

The catalog number for FTO Recombinant Rabbit Monoclonal Antibody [JM98-30] is ET1705-89.

What sizes are available for FTO Recombinant Rabbit Monoclonal Antibody [JM98-30]?

FTO Recombinant Rabbit Monoclonal Antibody [JM98-30] is available in the following size(s): 100 µL.

Is FTO Recombinant Rabbit Monoclonal Antibody [JM98-30] in stock?

FTO Recombinant Rabbit Monoclonal Antibody [JM98-30] is currently made to order / not held in immediate stock. Contact us for lead time.

What is FTO Recombinant Rabbit Monoclonal Antibody [JM98-30] used for?

FTO, also known as Fatso or KIAA1752, is a 505 amino acid protein that has an N-terminal nuclear localization signal. Expressed in a variety of tissues, with highest levels present in brain and pancreatic tissue, Fatso exists as four alternatively spliced isoforms, one of which is associated with a

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

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