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Product details

OPA1 Recombinant Rabbit Monoclonal Antibody [JM81-35]

Catalog number ET1705-9

Discontinued

Price for ET1705-9

Size / count 100 µL

This variant is discontinued and cannot be added to your cart.

About this product

Dynamin-related GTPase that is essential for normal mitochondrial morphology by regulating the equilibrium between mitochondrial fusion and mitochondrial fission .Coexpression of isoform 1 with shorter alternative products is required for optimal activity in promoting mitochondrial fusion.Binds lipid membranes enriched in negatively charged phospholipids, such as cardiolipin, and promotes membrane tubulation.The intrinsic GTPase activity is low, and is strongly increased by interaction with lipid membranes.Plays a role in remodeling cristae and the release of cytochrome c during apoptosis.Proteolytic processing in response to intrinsic apoptotic signals may lead to disassembly of OPA1 oligomers and release of the caspase activator cytochrome C (CYCS) into the mitochondrial intermembrane space. Plays a role in mitochondrial genome maintenance.

Specifications

Catalog number: ET1705-9
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
CAS Number: 9000-83-3
Product Name Alternative: Dynamin like 120 kDa protein antibody Dynamin like 120 kDa protein, mitochondrial antibody Dynamin-like 120 kDa protein, form S1 antibody FLJ12460 antibody Juvenile kjer type optic atrophy antibody KIAA0567 antibody KJER type antibody Large GTP binding protein antibody largeG antibody MGM1 antibody Mitochondrial dynamin like 120 kDa protein antibody Mitochondrial dynamin like GTPase antibody NPG antibody NTG antibody OAK antibody OPA 1 antibody opa1 antibody OPA1 gene antibody OPA1_HUMAN antibody Optic atrophy 1 (autosomal dominant) antibody OPTIC ATROPHY 1 antibody Optic atrophy 1 gene protein antibody Optic atrophy 1 homolog (human) antibody Optic atrophy protein 1 antibody Optic atrophy protein 1 homolog antibody
Abbreviation: OPA1
Swiss Prot: O60313 Human, P58281 Mouse, Q2TA68 Rat
Cellular Locus: Mitochondrion inner membrane. Mitochondrion intermembrane space.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within Human OPA1 aa 896-945 / 960.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Tissue, IHC-P, FC
Positive Control: Mouse testis tissue lysate, PC-12 cell lysate, mouse brain tissue lysate, Hela, SH-SY5Y, SW480, rat skeletal muscle tissue, human thyroid tissue, human kidney tissue, mouse brain tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:1,000 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 112 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for OPA1 Recombinant Rabbit Monoclonal Antibody [JM81-35]?

The catalog number for OPA1 Recombinant Rabbit Monoclonal Antibody [JM81-35] is ET1705-9.

Is OPA1 Recombinant Rabbit Monoclonal Antibody [JM81-35] in stock?

OPA1 Recombinant Rabbit Monoclonal Antibody [JM81-35] is currently made to order / not held in immediate stock. Contact us for lead time.

What is OPA1 Recombinant Rabbit Monoclonal Antibody [JM81-35] used for?

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.