Product details
Catalog number ET1705-94
Price for ET1705-94
Size / count 100 µL
Focal adhesions are identified as areas within the plasma membrane of tissue culture cells that adhere tightly to the underlying substrate. In vivo, these regions are involved in the adhesion of cells to the extracellular matrix. Paxillin and vinculin are cytoskeletal, focal adhesion proteins that are components of a protein complex which links the Actin network to the plasma membrane. Vinculin binding sites have been identified on other cytoskeletal proteins, including Talin and α-actinin. In addition, vinculin, Talin and α-actinin each contain Actin binding sites. Expression of vinculin and Talin have been shown to be affected by the level of Actin expression. α-Actinin has been shown to link Actin to integrins in the plasma membrane through interactions with the vinculin and Talin complex or by a direct interaction with integrin.
The catalog number for Vinculin Recombinant Rabbit Monoclonal Antibody [JM42-43] is ET1705-94.
Vinculin Recombinant Rabbit Monoclonal Antibody [JM42-43] is available in the following size(s): 100 µL.
Vinculin Recombinant Rabbit Monoclonal Antibody [JM42-43] is currently made to order / not held in immediate stock. Contact us for lead time.
Focal adhesions are identified as areas within the plasma membrane of tissue culture cells that adhere tightly to the underlying substrate. In vivo, these regions are involved in the adhesion of cells to the extracellular matrix. Paxillin and vinculin are cytoskeletal, focal adhesion proteins that a
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Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.
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