MMP-3 Recombinant Rabbit Monoclonal Antibody [JM46-22] — image 1 of 3

Product details

MMP-3 Recombinant Rabbit Monoclonal Antibody [JM46-22]

Catalog number ET1705-98

Price for ET1705-98

Size / count 100 µL

About this product

The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-3, MMP-10 and MMP-11 (also designated stromelysin-1, -2 and -3 respectively) activate procollagenase. MMP-3 activation of procollagenase can occur via two pathways. Direct activation by MMP-3 is slow and activation by MMP-3 in conjunction with tissue or plasma proteinases is rapid. MMP-10 is expressed in small intestine, and at lower levels in lung and heart. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies.

Specifications

Catalog number: ET1705-98
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: CHDS6 antibody Matrix metalloproteinase 3 antibody Matrix metalloproteinase-3 antibody MGC126102 antibody MGC126103 antibody MGC126104 antibody MMP 3 antibody MMP-3 antibody MMP3 antibody MMP3_HUMAN antibody Proteoglycanase antibody SL-1 antibody SL1 antibody STMY antibody STMY1 antibody STR1 antibody Stromelysin 1 antibody Stromelysin-1 antibody Transin 1 antibody Transin-1 antibody
Abbreviation: SL-1, MMP-3, MMP3, STMY1
Swiss Prot: P08254 Human, P28862 Mouse, P03957 Rat
Cellular Locus: extracellular matrix.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within C-terminal human MMP3.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P
Positive Control: Human liver tissue lysate, rat liver tissue lysate, rat kidney tissue, human liver tissue, human placenta tissue, mouse liver tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:2,000 ;IHC-P: 1:50-1:200
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 54 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for MMP-3 Recombinant Rabbit Monoclonal Antibody [JM46-22]?

The catalog number for MMP-3 Recombinant Rabbit Monoclonal Antibody [JM46-22] is ET1705-98.

What sizes are available for MMP-3 Recombinant Rabbit Monoclonal Antibody [JM46-22]?

MMP-3 Recombinant Rabbit Monoclonal Antibody [JM46-22] is available in the following size(s): 100 µL.

Is MMP-3 Recombinant Rabbit Monoclonal Antibody [JM46-22] in stock?

MMP-3 Recombinant Rabbit Monoclonal Antibody [JM46-22] is currently made to order / not held in immediate stock. Contact us for lead time.

What is MMP-3 Recombinant Rabbit Monoclonal Antibody [JM46-22] used for?

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.