PDX1 Recombinant Rabbit Monoclonal Antibody [JM62-45] — image 1 of 3

Product details

PDX1 Recombinant Rabbit Monoclonal Antibody [JM62-45]

Catalog number ET1705-99

Price for ET1705-99

Size / count 100 µL

About this product

Activates insulin, somatostatin, glucokinase, islet amyloid polypeptide and glucose transporter type 2 gene transcription. Particularly involved in glucose-dependent regulation of insulin gene transcription. As part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer; the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element. Binds preferentially the DNA motif 5'-[CT]TAAT[TG]-3'. During development, specifies the early pancreatic epithelium, permitting its proliferation, branching and subsequent differentiation. At adult stage, required for maintaining the hormone-producing phenotype of the beta-cell.

Specifications

Catalog number: ET1705-99
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: Glucose sensitive factor antibody Glucose-sensitive factor antibody GSF antibody IDX 1 antibody IDX-1 antibody IDX1 antibody Insulin promoter factor 1 antibody Insulin promoter factor 1 homeodomain transcription factor antibody Insulin upstream factor 1 antibody IPF 1 antibody IPF-1 antibody IPF1 antibody Islet/duodenum homeobox 1 antibody Islet/duodenum homeobox-1 antibody IUF 1 antibody IUF-1 antibody IUF1 antibody MODY4 antibody Pancreas/duodenum homeobox 1 antibody Pancreas/duodenum homeobox protein 1 antibody pancreatic and duodenal homeobox P antibody PDX 1 antibody PDX-1 antibody PDX1 antibody PDX1_HUMAN antibody Somatostatin transactivating factor 1 antibody Somatostatin-transactivating factor 1 antibody STF 1 antibody STF-1 antibody STF1 antibody
Abbreviation: PDX-1, GSF, IPF-1, IUF-1, IDX-1, STF-1
Swiss Prot: P52945 Human
Cellular Locus: Cytosol, Nucleus.
Host: Rabbit
Species Reactivity: Human
Immunogen: Synthetic peptide within Human PDX1 234-283 / 283.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P, IF-Cell, IF-Tissue
Positive Control: Hela cell lysates, human pancreas tissue, human gallbladder tissue, human stomach tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:1,000 ;IHC-P: 1:100-1:800 ;IF-Cell: 1:50-1:200 ;IF-Tissue: 1:50-1:200
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 31 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for PDX1 Recombinant Rabbit Monoclonal Antibody [JM62-45]?

The catalog number for PDX1 Recombinant Rabbit Monoclonal Antibody [JM62-45] is ET1705-99.

What sizes are available for PDX1 Recombinant Rabbit Monoclonal Antibody [JM62-45]?

PDX1 Recombinant Rabbit Monoclonal Antibody [JM62-45] is available in the following size(s): 100 µL.

Is PDX1 Recombinant Rabbit Monoclonal Antibody [JM62-45] in stock?

PDX1 Recombinant Rabbit Monoclonal Antibody [JM62-45] is currently made to order / not held in immediate stock. Contact us for lead time.

What is PDX1 Recombinant Rabbit Monoclonal Antibody [JM62-45] used for?

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.