Eg5 Recombinant Rabbit Monoclonal Antibody [JU83-16]

Catalog number ET1706-03

Price for ET1706-03

Size / count 100 µL

About this product

Eukaryotes contain a superfamily of microtubule-based motor proteins comprising kinesin and a number of related proteins that are thought to participate in various forms of intracellular motility, including cell division and organelle transport. KIF11 (also known as kinesin family member 11, Eg5 or TRIP5) is a slow, plus-end-directed microtubule-based motor of the BimC kinesin family that is essential for bipolar spindle formation during eukaryotic cell division. When the expression of KIF11 is blocked, centrosome migration halts and cells are arrested in mitosis with monoastral microtubule arrays. KIF11 is phosphorylated on serine during S phase and on both serine and Thr 927 during mitosis, which regulates the association of Eg5 with the spindle apparatus (probably during early prophase). KIF11 is also known to be a member of the thyroid receptor interacting protein (Trip) family, and interacts with the thyroid hormone receptor only in the presence of thyroid hormone.

Specifications

Catalog number: ET1706-03
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: EG5 antibody HKSP antibody KIF11 antibody KIF11_HUMAN antibody Kinesin family member 11 antibody Kinesin like protein 1 antibody Kinesin-like protein 1 antibody Kinesin-like protein KIF11 antibody Kinesin-like spindle protein HKSP antibody Kinesin-related motor protein Eg5 antibody KNSL1 antibody MCLMR antibody Thyroid receptor-interacting protein 5 antibody TR-interacting protein 5 antibody TRIP-5 antibody TRIP5 antibody
Abbreviation: TR-interacting protein 5, TRIP-5, KIF11, EG5, KNSL1, TRIP5
Swiss Prot: P52732 Human
Cellular Locus: Cytoplasm, Cytoskeleton, Microtubule.
Host: Rabbit
Species Reactivity: Human
Immunogen: Recombinant protein within Human Eg5 aa 860-1,056 / 1,056.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IP
Positive Control: A431 cell lysate, 293 cell lysate, Jurkat cell lysate.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:2,000 ;IP: 1:10-1:50
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 119 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Eg5 Recombinant Rabbit Monoclonal Antibody [JU83-16]?

The catalog number for Eg5 Recombinant Rabbit Monoclonal Antibody [JU83-16] is ET1706-03.

What sizes are available for Eg5 Recombinant Rabbit Monoclonal Antibody [JU83-16]?

Eg5 Recombinant Rabbit Monoclonal Antibody [JU83-16] is available in the following size(s): 100 µL.

Is Eg5 Recombinant Rabbit Monoclonal Antibody [JU83-16] in stock?

Eg5 Recombinant Rabbit Monoclonal Antibody [JU83-16] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Eg5 Recombinant Rabbit Monoclonal Antibody [JU83-16] used for?

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.